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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
17.27
Human Site:
T721
Identified Species:
27.14
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
T721
A
T
S
S
S
L
S
T
P
S
E
P
L
S
P
Chimpanzee
Pan troglodytes
XP_520790
703
80912
L687
N
I
K
S
P
F
S
L
S
H
V
P
H
G
K
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
T721
A
T
S
S
S
L
S
T
P
S
E
P
L
S
P
Dog
Lupus familis
XP_534869
703
80957
L687
N
I
K
S
P
F
S
L
G
R
V
P
R
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
T722
G
P
S
S
S
L
S
T
P
T
E
P
L
S
P
Rat
Rattus norvegicus
A2RRU1
738
84053
T722
G
P
S
S
S
L
S
T
P
T
E
P
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
S717
A
P
S
S
S
A
S
S
L
S
E
P
V
S
P
Chicken
Gallus gallus
XP_416432
704
81032
P685
D
R
Q
N
I
K
S
P
F
S
L
G
V
L
P
Frog
Xenopus laevis
NP_001084863
702
80811
F686
N
I
K
S
T
F
S
F
G
P
V
S
R
G
K
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
L685
N
I
R
Q
P
Y
N
L
P
N
R
N
K
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
P686
S
R
H
T
T
P
A
P
S
V
H
G
S
D
D
Honey Bee
Apis mellifera
XP_624707
692
79590
V677
G
S
D
E
E
D
E
V
D
D
E
K
E
L
E
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
T657
G
K
V
P
S
A
A
T
S
R
R
P
S
I
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
D693
L
S
T
N
G
A
I
D
N
D
D
D
D
N
D
Red Bread Mold
Neurospora crassa
O93869
706
80888
G691
L
K
Q
R
T
G
P
G
S
P
L
D
S
I
Q
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
20
100
20
N.A.
80
80
N.A.
66.6
20
13.3
6.6
N.A.
0
6.6
20
N.A.
P-Site Similarity:
100
20
100
20
N.A.
86.6
86.6
N.A.
80
33.3
20
26.6
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
20
14
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
7
0
7
7
14
7
14
7
7
14
% D
% Glu:
0
0
0
7
7
0
7
0
0
0
40
0
7
0
7
% E
% Phe:
0
0
0
0
0
20
0
7
7
0
0
0
0
0
0
% F
% Gly:
27
0
0
0
7
7
0
7
14
0
0
14
0
20
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
7
0
7
0
7
% H
% Ile:
0
27
0
0
7
0
7
0
0
0
0
0
0
14
0
% I
% Lys:
0
14
20
0
0
7
0
0
0
0
0
7
7
0
20
% K
% Leu:
14
0
0
0
0
27
0
20
7
0
14
0
27
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
27
0
0
14
0
0
7
0
7
7
0
7
0
14
0
% N
% Pro:
0
20
0
7
20
7
7
14
34
14
0
54
0
0
40
% P
% Gln:
0
0
14
7
0
0
0
0
0
0
0
0
0
0
14
% Q
% Arg:
0
14
7
7
0
0
0
0
0
14
14
0
14
0
0
% R
% Ser:
7
14
34
54
40
0
60
7
27
27
0
7
20
34
0
% S
% Thr:
0
14
7
7
20
0
0
34
0
14
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
7
0
7
20
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _