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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
26.67
Human Site:
Y102
Identified Species:
41.9
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
Y102
N
S
K
G
C
K
V
Y
F
G
R
W
L
I
E
Chimpanzee
Pan troglodytes
XP_520790
703
80912
H103
N
K
H
G
C
Q
V
H
F
G
R
W
L
I
E
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
Y102
N
S
K
G
C
K
V
Y
F
G
R
W
L
I
E
Dog
Lupus familis
XP_534869
703
80957
H103
N
K
H
G
C
Q
V
H
F
G
R
W
L
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
Y102
N
S
K
G
C
K
V
Y
F
G
R
W
L
I
E
Rat
Rattus norvegicus
A2RRU1
738
84053
Y102
N
S
K
G
C
K
V
Y
F
G
R
W
L
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
Y102
N
S
K
G
C
K
V
Y
Y
G
R
W
L
I
E
Chicken
Gallus gallus
XP_416432
704
81032
F103
K
S
Q
G
C
Q
V
F
F
G
R
W
L
I
E
Frog
Xenopus laevis
NP_001084863
702
80811
Y103
Q
S
Q
G
C
Q
V
Y
F
G
R
W
L
I
E
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
Y102
N
S
S
G
C
K
V
Y
F
G
R
W
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
M87
M
G
E
Q
L
C
M
M
G
P
Y
K
E
H
C
Honey Bee
Apis mellifera
XP_624707
692
79590
D88
R
T
E
V
E
E
A
D
F
P
H
N
N
P
L
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
L75
A
Q
I
S
T
E
E
L
G
D
Q
Y
C
M
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
V91
R
E
K
G
V
N
F
V
Y
G
N
W
L
I
E
Red Bread Mold
Neurospora crassa
O93869
706
80888
L89
R
D
R
G
I
G
I
L
Y
G
R
W
L
I
E
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
73.3
100
73.3
N.A.
100
100
N.A.
93.3
73.3
80
93.3
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
67
7
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% D
% Glu:
0
7
14
0
7
14
7
0
0
0
0
0
7
0
80
% E
% Phe:
0
0
0
0
0
0
7
7
67
0
0
0
0
0
7
% F
% Gly:
0
7
0
80
0
7
0
0
14
80
0
0
0
0
0
% G
% His:
0
0
14
0
0
0
0
14
0
0
7
0
0
7
0
% H
% Ile:
0
0
7
0
7
0
7
0
0
0
0
0
0
80
0
% I
% Lys:
7
14
40
0
0
40
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
14
0
0
0
0
80
0
7
% L
% Met:
7
0
0
0
0
0
7
7
0
0
0
0
0
7
0
% M
% Asn:
54
0
0
0
0
7
0
0
0
0
7
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
0
0
0
7
0
% P
% Gln:
7
7
14
7
0
27
0
0
0
0
7
0
0
0
0
% Q
% Arg:
20
0
7
0
0
0
0
0
0
0
74
0
0
0
0
% R
% Ser:
0
54
7
7
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
7
0
67
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
20
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _