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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
40.61
Human Site:
Y62
Identified Species:
63.81
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
Y62
G
D
E
W
G
D
N
Y
F
L
V
G
P
Y
T
Chimpanzee
Pan troglodytes
XP_520790
703
80912
Y63
A
D
E
W
G
E
N
Y
F
L
I
G
P
Y
F
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
Y62
G
D
E
W
G
D
N
Y
Y
L
V
G
P
Y
T
Dog
Lupus familis
XP_534869
703
80957
Y63
A
D
E
W
G
D
N
Y
F
L
I
G
P
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
Y62
G
D
E
W
G
D
N
Y
Y
L
V
G
P
Y
T
Rat
Rattus norvegicus
A2RRU1
738
84053
Y62
G
D
E
W
G
D
N
Y
Y
L
V
G
P
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
Y62
G
D
E
W
G
D
N
Y
Y
L
V
G
P
Y
T
Chicken
Gallus gallus
XP_416432
704
81032
Y63
A
D
E
W
G
E
N
Y
F
L
I
G
P
Y
F
Frog
Xenopus laevis
NP_001084863
702
80811
Y63
A
D
E
W
G
D
N
Y
F
L
M
G
P
Y
M
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
Y62
C
E
E
W
G
E
N
Y
F
L
V
G
P
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
E47
R
G
D
I
A
S
R
E
N
R
W
N
F
E
V
Honey Bee
Apis mellifera
XP_624707
692
79590
G48
W
E
A
A
N
K
V
G
G
I
Y
T
V
I
R
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
A35
E
E
V
L
E
M
D
A
G
Q
S
A
R
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
K51
T
L
L
G
P
L
N
K
A
T
Y
E
S
E
V
Red Bread Mold
Neurospora crassa
O93869
706
80888
Y49
T
A
E
Y
G
D
R
Y
T
L
I
G
P
L
N
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
73.3
93.3
80
N.A.
93.3
93.3
N.A.
93.3
73.3
80
73.3
N.A.
0
0
0
N.A.
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
100
N.A.
100
86.6
86.6
86.6
N.A.
6.6
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
7
7
7
7
0
0
7
7
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
7
0
0
54
7
0
0
0
0
0
0
0
0
% D
% Glu:
7
20
74
0
7
20
0
7
0
0
0
7
0
20
7
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
7
0
20
% F
% Gly:
34
7
0
7
74
0
0
7
14
0
0
74
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
27
0
0
7
0
% I
% Lys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
7
7
7
0
7
0
0
0
74
0
0
0
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
14
% M
% Asn:
0
0
0
0
7
0
74
0
7
0
0
7
0
0
7
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
74
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
14
0
0
7
0
0
7
0
7
% R
% Ser:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
0
% S
% Thr:
14
0
0
0
0
0
0
0
7
7
0
7
0
0
34
% T
% Val:
0
0
7
0
0
0
7
0
0
0
40
0
7
0
14
% V
% Trp:
7
0
0
67
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
74
27
0
14
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _