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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
9.39
Human Site:
S80
Identified Species:
13.78
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
S80
D
A
K
G
D
S
E
S
E
E
D
E
D
L
E
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
P154
G
E
E
E
E
A
A
P
A
D
A
G
A
F
N
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
P138
G
E
E
E
E
A
A
P
A
D
A
G
A
F
N
Dog
Lupus familis
XP_541890
401
45078
S77
D
A
K
A
D
S
E
S
E
D
D
E
D
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
D77
E
D
G
E
S
D
S
D
S
E
D
A
D
L
E
Rat
Rattus norvegicus
P12368
401
45522
D78
E
D
G
E
S
E
S
D
S
D
D
E
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
R47
H
P
K
T
D
D
Q
R
T
R
L
Q
E
A
C
Chicken
Gallus gallus
Q5ZM91
382
43332
E79
G
S
R
S
D
S
R
E
D
E
I
S
P
P
P
Frog
Xenopus laevis
NP_001084637
402
45172
E79
Q
T
D
S
E
N
G
E
E
D
E
E
D
F
V
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
E77
S
N
G
D
E
D
D
E
D
D
D
S
D
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
S84
M
A
S
S
R
R
K
S
V
F
A
E
A
Y
D
Honey Bee
Apis mellifera
XP_392905
383
43849
S85
K
L
A
T
R
R
K
S
V
F
A
E
T
Y
N
Nematode Worm
Caenorhab. elegans
P30625
366
41449
I72
A
A
D
D
D
D
I
I
V
E
P
P
K
R
S
Sea Urchin
Strong. purpuratus
Q26619
369
41770
S81
N
R
Y
A
R
R
K
S
V
C
A
E
K
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
A118
E
Q
D
T
H
Q
Q
A
Q
E
E
Q
Q
H
T
Red Bread Mold
Neurospora crassa
Q01386
385
42138
S91
L
G
R
R
T
S
V
S
A
E
S
L
K
P
V
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
0
0
80
N.A.
33.3
33.3
N.A.
13.3
20
20
20
N.A.
20
13.3
20
13.3
P-Site Similarity:
100
26.6
26.6
93.3
N.A.
40
46.6
N.A.
33.3
40
46.6
46.6
N.A.
33.3
20
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
7
13
0
13
13
7
19
0
32
7
19
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% C
% Asp:
13
13
19
13
32
25
7
13
13
38
32
0
38
0
19
% D
% Glu:
19
13
13
25
25
7
13
19
19
38
13
44
7
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
0
0
25
0
% F
% Gly:
19
7
19
7
0
0
7
0
0
0
0
13
0
0
0
% G
% His:
7
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% I
% Lys:
7
0
19
0
0
0
19
0
0
0
0
0
19
0
0
% K
% Leu:
7
7
0
0
0
0
0
0
0
0
7
7
0
25
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
7
0
0
0
0
0
0
0
0
19
% N
% Pro:
0
7
0
0
0
0
0
13
0
0
7
7
7
13
7
% P
% Gln:
7
7
0
0
0
7
13
0
7
0
0
13
7
0
0
% Q
% Arg:
0
7
13
7
19
19
7
7
0
7
0
0
0
7
0
% R
% Ser:
7
7
7
19
13
25
13
38
13
0
7
13
0
0
7
% S
% Thr:
0
7
0
19
7
0
0
0
7
0
0
0
7
0
7
% T
% Val:
0
0
0
0
0
0
7
0
25
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _