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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
17.88
Human Site:
S92
Identified Species:
26.22
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
S92
D
L
E
V
P
V
P
S
R
F
N
R
R
V
S
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
N166
A
F
N
A
P
V
I
N
R
F
T
R
R
A
S
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
N150
A
F
N
A
P
V
I
N
R
F
T
R
R
A
S
Dog
Lupus familis
XP_541890
401
45078
S89
D
L
D
V
P
I
P
S
R
F
D
R
R
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
S89
D
L
E
V
P
V
P
S
K
F
T
R
R
V
S
Rat
Rattus norvegicus
P12368
401
45522
S90
D
L
E
V
P
I
P
S
K
F
T
R
R
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
L59
E
A
C
K
D
I
L
L
F
K
N
L
D
P
E
Chicken
Gallus gallus
Q5ZM91
382
43332
V91
P
P
P
P
M
N
P
V
V
K
G
R
R
R
R
Frog
Xenopus laevis
NP_001084637
402
45172
N91
D
F
V
A
P
V
I
N
R
F
S
R
R
A
S
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S89
D
F
E
P
P
P
P
S
R
F
N
R
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
D96
A
Y
D
P
E
A
D
D
D
D
D
G
A
T
A
Honey Bee
Apis mellifera
XP_392905
383
43849
E97
T
Y
N
P
E
E
D
E
E
D
D
G
L
K
I
Nematode Worm
Caenorhab. elegans
P30625
366
41449
T84
K
R
S
G
G
R
R
T
G
I
S
A
E
P
I
Sea Urchin
Strong. purpuratus
Q26619
369
41770
N93
K
Y
D
P
E
A
D
N
D
T
D
T
Q
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
S130
Q
H
T
R
E
K
T
S
T
P
P
L
P
M
H
Red Bread Mold
Neurospora crassa
Q01386
385
42138
D103
K
P
V
T
D
N
S
D
N
W
S
P
P
V
H
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
46.6
46.6
80
N.A.
86.6
80
N.A.
6.6
20
53.3
80
N.A.
0
0
0
0
P-Site Similarity:
100
53.3
53.3
100
N.A.
93.3
93.3
N.A.
20
20
66.6
80
N.A.
20
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
19
0
13
0
0
0
0
0
7
7
19
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
38
0
19
0
13
0
19
13
13
13
25
0
7
0
0
% D
% Glu:
7
0
25
0
25
7
0
7
7
0
0
0
7
0
7
% E
% Phe:
0
25
0
0
0
0
0
0
7
50
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
0
0
0
7
0
7
13
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
19
19
0
0
7
0
0
0
0
13
% I
% Lys:
19
0
0
7
0
7
0
0
13
13
0
0
0
13
0
% K
% Leu:
0
25
0
0
0
0
7
7
0
0
0
13
7
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
19
0
0
13
0
25
7
0
19
0
0
0
0
% N
% Pro:
7
13
7
32
50
7
38
0
0
7
7
7
13
13
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
7
0
7
0
7
7
0
38
0
0
57
57
7
7
% R
% Ser:
0
0
7
0
0
0
7
38
0
0
19
0
0
0
50
% S
% Thr:
7
0
7
7
0
0
7
7
7
7
25
7
0
7
0
% T
% Val:
0
0
13
25
0
32
0
7
7
0
0
0
0
38
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _