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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO3
All Species:
26.36
Human Site:
S176
Identified Species:
44.62
UniProt:
P13929
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13929
NP_001967.2
434
46932
S176
M
I
L
P
V
G
A
S
S
F
K
E
A
M
R
Chimpanzee
Pan troglodytes
XP_511294
434
46968
S176
M
I
L
P
V
G
A
S
S
F
K
E
A
M
R
Rhesus Macaque
Macaca mulatta
XP_001098883
434
47136
A176
M
I
L
P
V
G
A
A
N
F
R
E
A
M
R
Dog
Lupus familis
XP_536606
434
47036
S176
M
I
L
P
V
G
A
S
S
F
R
E
A
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P21550
434
47006
S176
M
I
L
P
V
G
A
S
S
F
K
E
A
M
R
Rat
Rattus norvegicus
P15429
434
46995
S176
M
I
L
P
V
G
A
S
S
F
K
E
A
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
E176
M
I
L
P
I
G
A
E
S
F
K
E
A
M
R
Chicken
Gallus gallus
P07322
434
47178
A176
M
V
L
P
V
G
A
A
S
F
H
D
A
M
R
Frog
Xenopus laevis
P08734
434
47486
D176
M
I
L
P
V
G
A
D
S
F
K
E
A
M
R
Zebra Danio
Brachydanio rerio
NP_999888
433
47454
Q176
M
I
L
P
V
G
A
Q
N
F
H
E
A
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
T243
M
I
L
P
T
G
A
T
S
F
T
E
A
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
S176
M
I
L
P
V
G
A
S
S
F
A
E
A
M
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
A182
M
I
L
P
T
G
A
A
S
F
K
E
A
M
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
A181
M
I
L
P
V
G
A
A
S
F
K
E
A
M
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
83.1
98.1
N.A.
97.4
97.9
N.A.
78.5
85
83.1
85.2
N.A.
63.7
N.A.
73
N.A.
Protein Similarity:
100
99.7
91.2
99.3
N.A.
99.3
99.3
N.A.
86.3
92.1
90.5
92.6
N.A.
72.5
N.A.
83.6
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
100
100
N.A.
86.6
73.3
93.3
80
N.A.
73.3
N.A.
93.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
86.6
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
68.8
N.A.
69.8
N.A.
N.A.
Protein Similarity:
N.A.
80
N.A.
79.9
N.A.
N.A.
P-Site Identity:
N.A.
80
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
100
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
100
29
0
0
8
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
93
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
93
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
58
0
0
0
22
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
100
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
79
% R
% Ser:
0
0
0
0
0
0
0
43
86
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
8
0
0
8
0
0
0
0
% T
% Val:
0
8
0
0
79
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _