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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO3
All Species:
39.09
Human Site:
S263
Identified Species:
66.15
UniProt:
P13929
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13929
NP_001967.2
434
46932
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Chimpanzee
Pan troglodytes
XP_511294
434
46968
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Rhesus Macaque
Macaca mulatta
XP_001098883
434
47136
S263
K
Y
D
L
D
F
K
S
P
D
D
P
S
R
Y
Dog
Lupus familis
XP_536606
434
47036
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Cat
Felis silvestris
Mouse
Mus musculus
P21550
434
47006
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Rat
Rattus norvegicus
P15429
434
46995
S263
K
Y
D
L
D
F
K
S
P
D
D
P
A
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
S263
K
Y
D
L
D
F
K
S
P
D
D
P
S
R
Y
Chicken
Gallus gallus
P07322
434
47178
S263
R
Y
H
L
D
F
K
S
P
P
H
T
K
R
Y
Frog
Xenopus laevis
P08734
434
47486
S263
K
Y
D
L
D
F
K
S
P
D
D
P
S
R
Y
Zebra Danio
Brachydanio rerio
NP_999888
433
47454
S263
K
Y
D
L
D
F
K
S
P
D
D
P
K
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
E331
Y
D
L
D
F
K
N
E
K
S
D
K
S
Q
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
P264
Y
D
L
D
F
K
N
P
A
S
D
S
S
K
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
E272
Y
D
L
N
F
K
E
E
N
N
D
G
S
Q
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
E270
Y
D
L
N
F
K
E
E
N
N
N
G
S
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
83.1
98.1
N.A.
97.4
97.9
N.A.
78.5
85
83.1
85.2
N.A.
63.7
N.A.
73
N.A.
Protein Similarity:
100
99.7
91.2
99.3
N.A.
99.3
99.3
N.A.
86.3
92.1
90.5
92.6
N.A.
72.5
N.A.
83.6
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
86.6
53.3
86.6
93.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
66.6
100
93.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
68.8
N.A.
69.8
N.A.
N.A.
Protein Similarity:
N.A.
80
N.A.
79.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
36
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
65
15
72
0
0
0
0
65
86
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
15
22
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
29
72
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
43
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
65
0
0
0
0
29
72
0
8
0
0
8
15
8
15
% K
% Leu:
0
0
29
72
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
15
0
15
15
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
72
8
0
65
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% R
% Ser:
0
0
0
0
0
0
0
72
0
15
0
8
50
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
29
72
0
0
0
0
0
0
0
0
0
0
0
0
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _