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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO3
All Species:
52.42
Human Site:
Y280
Identified Species:
88.72
UniProt:
P13929
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13929
NP_001967.2
434
46932
Y280
G
E
K
L
G
E
L
Y
K
S
F
I
K
N
Y
Chimpanzee
Pan troglodytes
XP_511294
434
46968
Y280
G
E
K
L
G
E
L
Y
K
S
F
I
K
N
Y
Rhesus Macaque
Macaca mulatta
XP_001098883
434
47136
Y280
P
D
Q
L
A
D
L
Y
K
S
F
I
K
D
Y
Dog
Lupus familis
XP_536606
434
47036
Y280
G
E
K
L
G
E
L
Y
K
S
F
I
K
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
P21550
434
47006
Y280
G
E
K
L
G
E
L
Y
K
N
F
I
Q
N
Y
Rat
Rattus norvegicus
P15429
434
46995
Y280
G
E
K
L
G
E
L
Y
K
S
F
I
K
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
Y280
P
D
Q
L
G
D
L
Y
K
T
F
I
K
N
Y
Chicken
Gallus gallus
P07322
434
47178
Y280
G
E
Q
L
G
E
I
Y
R
G
F
I
K
D
Y
Frog
Xenopus laevis
P08734
434
47486
Y280
P
D
K
L
A
E
L
Y
M
S
F
V
K
N
Y
Zebra Danio
Brachydanio rerio
NP_999888
433
47454
Y280
G
E
Q
L
G
D
L
Y
K
S
F
I
K
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
Y348
A
D
K
L
A
N
L
Y
Q
E
F
I
K
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
Y281
G
E
Q
L
T
E
L
Y
Q
S
F
I
K
E
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
Y289
G
D
S
L
K
N
V
Y
K
S
F
V
S
E
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
Y287
G
D
A
L
K
D
L
Y
K
S
F
V
A
E
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
83.1
98.1
N.A.
97.4
97.9
N.A.
78.5
85
83.1
85.2
N.A.
63.7
N.A.
73
N.A.
Protein Similarity:
100
99.7
91.2
99.3
N.A.
99.3
99.3
N.A.
86.3
92.1
90.5
92.6
N.A.
72.5
N.A.
83.6
N.A.
P-Site Identity:
100
100
60
100
N.A.
86.6
100
N.A.
66.6
66.6
66.6
86.6
N.A.
46.6
N.A.
73.3
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
93.3
80
100
N.A.
73.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
68.8
N.A.
69.8
N.A.
N.A.
Protein Similarity:
N.A.
80
N.A.
79.9
N.A.
N.A.
P-Site Identity:
N.A.
46.6
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
22
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
43
0
0
0
29
0
0
0
0
0
0
0
22
0
% D
% Glu:
0
58
0
0
0
58
0
0
0
8
0
0
0
22
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
8
% F
% Gly:
72
0
0
0
58
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
79
0
0
0
% I
% Lys:
0
0
50
0
15
0
0
0
72
0
0
0
79
0
0
% K
% Leu:
0
0
0
100
0
0
86
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
8
0
0
0
58
0
% N
% Pro:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
36
0
0
0
0
0
15
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
72
0
0
8
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
93
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _