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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRB3
All Species:
20.61
Human Site:
S255
Identified Species:
50.37
UniProt:
P13945
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13945
NP_000016.1
408
43519
S255
E
E
S
P
P
A
P
S
R
S
L
A
P
A
P
Chimpanzee
Pan troglodytes
XP_519708
408
43486
S255
E
E
S
P
P
A
P
S
R
S
L
A
P
A
P
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
S255
E
E
S
S
P
A
L
S
R
S
L
A
P
A
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P25962
400
42988
S252
E
E
S
P
P
S
P
S
R
S
P
S
P
A
T
Rat
Rattus norvegicus
P26255
400
43128
S252
E
E
S
P
R
S
P
S
R
S
P
S
P
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513543
477
52086
P290
P
P
A
P
P
A
P
P
P
P
P
P
R
S
P
Chicken
Gallus gallus
XP_428541
514
55555
S326
Q
E
T
P
S
L
S
S
R
A
G
R
R
R
R
Frog
Xenopus laevis
O42574
385
43291
S250
F
S
H
S
H
V
L
S
H
G
R
S
S
R
R
Zebra Danio
Brachydanio rerio
NP_001122161
390
43773
N240
F
Y
N
N
H
G
T
N
C
K
P
T
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q4LBB9
536
60360
S375
Q
P
S
G
E
A
L
S
G
S
G
S
S
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
87.8
N.A.
N.A.
79.9
78.9
N.A.
47.7
49
44.6
44.3
N.A.
28.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
89.2
N.A.
N.A.
83.8
83.3
N.A.
56.8
59.3
58.8
58.5
N.A.
39.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
73.3
66.6
N.A.
33.3
26.6
6.6
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
N.A.
N.A.
86.6
80
N.A.
46.6
46.6
13.3
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
50
0
0
0
10
0
30
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
60
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
10
20
0
0
0
0
% G
% His:
0
0
10
0
20
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% K
% Leu:
0
0
0
0
0
10
30
0
0
0
30
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
20
0
60
50
0
50
10
10
10
40
10
50
0
40
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
60
0
10
10
30
20
30
% R
% Ser:
0
10
60
20
10
20
10
80
0
60
0
40
20
10
0
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
30
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _