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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD59 All Species: 1.21
Human Site: Y87 Identified Species: 4.44
UniProt: P13987 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13987 NP_000602.1 128 14177 Y87 R E N E L T Y Y C C K K D L C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082615 128 14017 F87 K E S E L R Y F C C K K D L C
Dog Lupus familis XP_533156 123 13774 K84 S N S F Q I K K L E Y Y C C Q
Cat Felis silvestris
Mouse Mus musculus P58019 129 14247 L91 S K C C Q W G L C N K N L D G
Rat Rattus norvegicus P27274 126 13772 A88 V Q Y R C C Q A D L C N K S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421075 127 14134 Q87 N D I A V F Y Q L D N F D Y F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665541 127 13698 Y88 A N S S T Q I Y Q M T K T C C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.3 46.8 N.A. 40.3 46 N.A. N.A. 36.7 N.A. 28.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 92.9 62.5 N.A. 51.1 59.3 N.A. N.A. 53.1 N.A. 40.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 73.3 0 N.A. 13.3 0 N.A. N.A. 13.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 6.6 N.A. 20 6.6 N.A. N.A. 26.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 15 0 0 0 15 0 0 0 0 0 0 0 % A
% Cys: 0 0 15 15 15 15 0 0 43 29 15 0 15 29 43 % C
% Asp: 0 15 0 0 0 0 0 0 15 15 0 0 43 15 0 % D
% Glu: 0 29 0 29 0 0 0 0 0 15 0 0 0 0 0 % E
% Phe: 0 0 0 15 0 15 0 15 0 0 0 15 0 0 29 % F
% Gly: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 0 15 15 0 0 0 0 0 0 0 0 % I
% Lys: 15 15 0 0 0 0 15 15 0 0 43 43 15 0 0 % K
% Leu: 0 0 0 0 29 0 0 15 29 15 0 0 15 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % M
% Asn: 15 29 15 0 0 0 0 0 0 15 15 29 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 0 0 29 15 15 15 15 0 0 0 0 0 15 % Q
% Arg: 15 0 0 15 0 15 0 0 0 0 0 0 0 0 0 % R
% Ser: 29 0 43 15 0 0 0 0 0 0 0 0 0 15 0 % S
% Thr: 0 0 0 0 15 15 0 0 0 0 15 0 15 0 0 % T
% Val: 15 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 43 29 0 0 15 15 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _