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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC130 All Species: 9.39
Human Site: S252 Identified Species: 15.9
UniProt: P13994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13994 NP_110445.1 396 44802 S252 L K R T E I I S R S W F P S A
Chimpanzee Pan troglodytes XP_001156507 529 58949 S385 L K R T E I I S R S W F P S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542031 397 45019 S252 L K R S E I I S R S W F P S T
Cat Felis silvestris
Mouse Mus musculus Q9D516 385 43862 K242 T L D S Y E D K Q R M K R T E
Rat Rattus norvegicus Q32PZ9 385 43782 K242 T L D S Y E D K Q R M K R T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DJK9 384 43902 E240 Y R S L E S Y E Q K Q K K K R
Zebra Danio Brachydanio rerio Q66I85 390 43749 K243 P D S Y E D K K Q W K R Q E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K0F0 316 36322 S174 K L V E R N M S V W D D S Y M
Honey Bee Apis mellifera XP_623589 312 36201 A170 S S L E S A I A L N D A T W K
Nematode Worm Caenorhab. elegans Q09651 369 42122 R227 P E T E E D R R I A S M M T R
Sea Urchin Strong. purpuratus XP_782025 604 66489 N258 Q K R E S I Q N R N I F A P S
Poplar Tree Populus trichocarpa XP_002311431 313 35348 Q171 E P V L V R L Q R V S D A R H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173930 310 35035 V168 K A A E P L L V R L Q R V S D
Baker's Yeast Sacchar. cerevisiae P28320 278 32293 E136 T A V E S I D E T L Q R L V R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 N.A. 87.4 N.A. 78.7 77.5 N.A. N.A. N.A. 60 58.8 N.A. 44.7 42.9 38.8 40.4
Protein Similarity: 100 74.4 N.A. 90.1 N.A. 84 82.3 N.A. N.A. N.A. 71.4 71.7 N.A. 57 56.5 55.5 49
P-Site Identity: 100 100 N.A. 86.6 N.A. 0 0 N.A. N.A. N.A. 6.6 6.6 N.A. 6.6 6.6 6.6 33.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 20 20 N.A. N.A. N.A. 20 13.3 N.A. 13.3 20 26.6 53.3
Percent
Protein Identity: 37.8 N.A. N.A. 36.8 25.2 N.A.
Protein Similarity: 50.7 N.A. N.A. 50.2 39.1 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 8 0 8 0 8 0 8 15 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 0 0 15 22 0 0 0 15 15 0 0 8 % D
% Glu: 8 8 0 43 43 15 0 15 0 0 0 0 0 8 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 36 29 0 8 0 8 0 0 0 8 % I
% Lys: 15 29 0 0 0 0 8 22 0 8 8 22 8 8 8 % K
% Leu: 22 22 8 15 0 8 15 0 8 15 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 15 8 8 0 8 % M
% Asn: 0 0 0 0 0 8 0 8 0 15 0 0 0 0 0 % N
% Pro: 15 8 0 0 8 0 0 0 0 0 0 0 22 8 0 % P
% Gln: 8 0 0 0 0 0 8 8 29 0 22 0 8 0 0 % Q
% Arg: 0 8 29 0 8 8 8 8 43 15 0 22 15 8 22 % R
% Ser: 8 8 15 22 22 8 0 29 0 22 15 0 8 29 8 % S
% Thr: 22 0 8 15 0 0 0 0 8 0 0 0 8 22 8 % T
% Val: 0 0 22 0 8 0 0 8 8 8 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 15 22 0 0 8 0 % W
% Tyr: 8 0 0 8 15 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _