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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC130 All Species: 6.97
Human Site: S269 Identified Species: 11.79
UniProt: P13994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13994 NP_110445.1 396 44802 S269 S A S S S K V S G V L K K L A
Chimpanzee Pan troglodytes XP_001156507 529 58949 S402 S A S S S K V S G V L K K L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542031 397 45019 A269 P A T S S S K A G S V L K K L
Cat Felis silvestris
Mouse Mus musculus Q9D516 385 43862 A259 H R S W F P S A Q G P S A S S
Rat Rattus norvegicus Q32PZ9 385 43782 A259 H R S W F P S A Q G P S T S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DJK9 384 43902 S257 I C N R S W F S P G V D S G Q
Zebra Danio Brachydanio rerio Q66I85 390 43749 S260 R S W F N S P S S A A G G A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K0F0 316 36322 R191 S R L R A E F R Q Q K K E I N
Honey Bee Apis mellifera XP_623589 312 36201 R187 Y T S N C A L R T A F R T R K
Nematode Worm Caenorhab. elegans Q09651 369 42122 H244 D T K T H D D H L E S S R D R
Sea Urchin Strong. purpuratus XP_782025 604 66489 I275 S S P N S I E I S P R S S S S
Poplar Tree Populus trichocarpa XP_002311431 313 35348 L188 D Y A L N K A L R A R M R S H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173930 310 35035 N185 H A D D Y S L N K A L R A Q L
Baker's Yeast Sacchar. cerevisiae P28320 278 32293 M153 E M E Q N E K M G I K E Q A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 N.A. 87.4 N.A. 78.7 77.5 N.A. N.A. N.A. 60 58.8 N.A. 44.7 42.9 38.8 40.4
Protein Similarity: 100 74.4 N.A. 90.1 N.A. 84 82.3 N.A. N.A. N.A. 71.4 71.7 N.A. 57 56.5 55.5 49
P-Site Identity: 100 100 N.A. 33.3 N.A. 6.6 6.6 N.A. N.A. N.A. 13.3 13.3 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 100 N.A. 53.3 N.A. 20 20 N.A. N.A. N.A. 26.6 26.6 N.A. 40 26.6 13.3 33.3
Percent
Protein Identity: 37.8 N.A. N.A. 36.8 25.2 N.A.
Protein Similarity: 50.7 N.A. N.A. 50.2 39.1 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 8 0 8 8 8 22 0 29 8 0 15 15 22 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 8 8 0 8 8 0 0 0 0 8 0 8 8 % D
% Glu: 8 0 8 0 0 15 8 0 0 8 0 8 8 0 0 % E
% Phe: 0 0 0 8 15 0 15 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 29 22 0 8 8 8 0 % G
% His: 22 0 0 0 8 0 0 8 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 8 0 8 0 8 0 0 0 8 0 % I
% Lys: 0 0 8 0 0 22 15 0 8 0 15 22 22 8 8 % K
% Leu: 0 0 8 8 0 0 15 8 8 0 22 8 0 15 15 % L
% Met: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 15 22 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 8 0 8 0 0 15 8 0 8 8 15 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 22 8 0 0 8 8 8 % Q
% Arg: 8 22 0 15 0 0 0 15 8 0 15 15 15 8 8 % R
% Ser: 29 15 36 22 36 22 15 29 15 8 8 29 15 29 22 % S
% Thr: 0 15 8 8 0 0 0 0 8 0 0 0 15 0 0 % T
% Val: 0 0 0 0 0 0 15 0 0 15 15 0 0 0 0 % V
% Trp: 0 0 8 15 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _