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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC130 All Species: 8.18
Human Site: T281 Identified Species: 13.85
UniProt: P13994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13994 NP_110445.1 396 44802 T281 K L A Q S R R T A L A T S P I
Chimpanzee Pan troglodytes XP_001156507 529 58949 T414 K L A Q S R R T A L A T C P I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542031 397 45019 R281 K K L A Q N R R S A P A S S P
Cat Felis silvestris
Mouse Mus musculus Q9D516 385 43862 S271 A S S S K A S S V L K K L C Q
Rat Rattus norvegicus Q32PZ9 385 43782 T271 T S S S K A S T V L K K L C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DJK9 384 43902 N269 S G Q Q A P G N T M R K L G I
Zebra Danio Brachydanio rerio Q66I85 390 43749 Q272 G A A G S L L Q K L G Q Q G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K0F0 316 36322 L203 E I N G Q Q E L D R Q L L A K
Honey Bee Apis mellifera XP_623589 312 36201 K199 T R K K E L Q K K Q S L D Q I
Nematode Worm Caenorhab. elegans Q09651 369 42122 R256 R D R I E S R R I F R R P E E
Sea Urchin Strong. purpuratus XP_782025 604 66489 S287 S S S H S S P S S S S S S K K
Poplar Tree Populus trichocarpa XP_002311431 313 35348 A200 R S H K K R V A E E E S T S R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173930 310 35035 K197 A Q L R R H R K R V A E E E T
Baker's Yeast Sacchar. cerevisiae P28320 278 32293 L165 Q A D D K M D L L E K R L A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 N.A. 87.4 N.A. 78.7 77.5 N.A. N.A. N.A. 60 58.8 N.A. 44.7 42.9 38.8 40.4
Protein Similarity: 100 74.4 N.A. 90.1 N.A. 84 82.3 N.A. N.A. N.A. 71.4 71.7 N.A. 57 56.5 55.5 49
P-Site Identity: 100 93.3 N.A. 20 N.A. 6.6 13.3 N.A. N.A. N.A. 13.3 20 N.A. 0 6.6 6.6 13.3
P-Site Similarity: 100 93.3 N.A. 26.6 N.A. 20 20 N.A. N.A. N.A. 26.6 20 N.A. 20 26.6 13.3 46.6
Percent
Protein Identity: 37.8 N.A. N.A. 36.8 25.2 N.A.
Protein Similarity: 50.7 N.A. N.A. 50.2 39.1 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 22 8 8 15 0 8 15 8 22 8 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % C
% Asp: 0 8 8 8 0 0 8 0 8 0 0 0 8 0 0 % D
% Glu: 8 0 0 0 15 0 8 0 8 15 8 8 8 15 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 8 0 15 0 0 8 0 0 0 8 0 0 15 0 % G
% His: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 29 % I
% Lys: 22 8 8 15 29 0 0 15 15 0 22 22 0 8 22 % K
% Leu: 0 15 15 0 0 15 8 15 8 36 0 15 36 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 8 0 0 0 8 0 8 15 8 % P
% Gln: 8 8 8 22 15 8 8 8 0 8 8 8 8 8 8 % Q
% Arg: 15 8 8 8 8 22 36 15 8 8 15 15 0 0 22 % R
% Ser: 15 29 22 15 29 15 15 15 15 8 15 15 22 15 0 % S
% Thr: 15 0 0 0 0 0 0 22 8 0 0 15 8 0 8 % T
% Val: 0 0 0 0 0 0 8 0 15 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _