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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD3B1
All Species:
13.33
Human Site:
S248
Identified Species:
32.59
UniProt:
P14060
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14060
NP_000853.1
373
42252
S248
Q
D
P
K
K
A
P
S
I
R
G
Q
F
Y
Y
Chimpanzee
Pan troglodytes
XP_524830
375
42486
S250
Q
D
P
K
K
A
P
S
I
R
G
Q
F
Y
Y
Rhesus Macaque
Macaca mulatta
P27365
373
41987
S248
R
D
P
K
K
A
P
S
V
Q
G
Q
F
Y
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P24815
373
42044
S248
R
D
P
K
K
S
T
S
I
Q
G
Q
F
Y
Y
Rat
Rattus norvegicus
Q62878
373
41939
N248
R
D
P
K
K
S
Q
N
V
Q
G
Q
F
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511034
347
38904
R222
R
D
P
E
R
A
P
R
L
G
G
Q
F
F
F
Chicken
Gallus gallus
NP_990449
377
42863
H252
Q
V
P
Q
K
A
R
H
I
R
G
Q
F
Y
Y
Frog
Xenopus laevis
Q0IH73
386
43592
K241
E
A
L
T
S
E
K
K
Y
I
A
A
G
Q
P
Zebra Danio
Brachydanio rerio
A8DZE7
387
43577
Q241
D
A
L
T
E
K
Q
Q
C
R
A
A
G
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53199
349
38688
V222
D
W
T
Y
A
G
N
V
A
D
A
H
V
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
93.8
N.A.
N.A.
71.5
73.1
N.A.
50.1
57
30.5
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97.5
N.A.
N.A.
84.7
84.7
N.A.
67.5
71
48.1
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
N.A.
N.A.
73.3
60
N.A.
46.6
73.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
86.6
80
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
10
50
0
0
10
0
30
20
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
20
60
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
70
10
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
70
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
40
10
0
0
0
0
0
% I
% Lys:
0
0
0
50
60
10
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
20
0
0
0
0
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
0
0
0
40
0
0
0
0
0
0
0
10
% P
% Gln:
30
0
0
10
0
0
20
10
0
30
0
70
0
20
0
% Q
% Arg:
40
0
0
0
10
0
10
10
0
40
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
20
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
20
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
10
20
0
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
10
0
0
0
0
60
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _