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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFAP
All Species:
25.15
Human Site:
T180
Identified Species:
69.17
UniProt:
P14136
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14136
NP_001124491.1
432
49880
T180
R
Q
E
A
D
E
A
T
L
A
R
L
D
L
E
Chimpanzee
Pan troglodytes
Q5R1W8
466
53634
S214
R
Q
D
V
D
N
A
S
L
A
R
L
D
L
E
Rhesus Macaque
Macaca mulatta
XP_001102095
360
41153
N143
R
L
E
V
E
R
D
N
L
A
Q
D
L
G
T
Dog
Lupus familis
XP_848378
433
49999
T181
R
Q
E
A
D
E
A
T
L
A
R
L
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P03995
430
49882
T177
R
Q
E
A
D
E
A
T
L
A
R
V
D
L
E
Rat
Rattus norvegicus
P47819
430
49939
T178
R
Q
E
A
D
E
A
T
L
A
R
V
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09654
460
53124
S208
R
Q
D
V
D
N
A
S
L
A
G
L
D
L
E
Frog
Xenopus laevis
P24790
463
53478
S208
R
Q
D
V
D
N
A
S
L
A
R
I
D
L
E
Zebra Danio
Brachydanio rerio
Q58EE9
444
51231
A192
R
Q
D
V
D
E
A
A
L
N
R
V
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.5
78.4
93.5
N.A.
91.1
91.4
N.A.
N.A.
53.7
53.7
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.6
80.3
96
N.A.
95.8
94.9
N.A.
N.A.
75
73.2
77.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
26.6
100
N.A.
93.3
93.3
N.A.
N.A.
66.6
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
40
100
N.A.
100
100
N.A.
N.A.
80
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
0
0
89
12
0
89
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
45
0
89
0
12
0
0
0
0
12
78
0
0
% D
% Glu:
0
0
56
0
12
56
0
0
0
0
0
0
0
0
89
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
100
0
0
45
12
89
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
34
0
12
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
89
0
0
0
0
0
0
0
0
12
0
12
0
0
% Q
% Arg:
100
0
0
0
0
12
0
0
0
0
78
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
12
% T
% Val:
0
0
0
56
0
0
0
0
0
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _