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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIF
All Species:
19.39
Human Site:
S91
Identified Species:
47.41
UniProt:
P14174
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14174
NP_002406.1
115
12476
S91
L
A
E
R
L
R
I
S
P
D
R
V
Y
I
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849796
113
12155
P90
A
P
P
S
R
G
P
P
H
P
N
R
D
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P34884
115
12486
S91
L
S
D
R
L
H
I
S
P
D
R
V
Y
I
N
Rat
Rattus norvegicus
P30904
115
12459
S91
L
S
D
R
L
H
I
S
P
D
R
V
Y
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507338
115
12219
P91
L
T
K
H
L
N
I
P
A
D
R
V
Y
I
N
Chicken
Gallus gallus
Q02960
115
12466
S91
I
A
K
H
L
H
V
S
A
D
R
V
Y
I
N
Frog
Xenopus laevis
Q76BK2
115
12482
P91
L
T
K
Q
L
N
I
P
A
N
R
V
Y
I
N
Zebra Danio
Brachydanio rerio
NP_001036786
115
12394
S91
L
N
K
H
L
G
V
S
A
D
R
I
Y
I
N
Tiger Blowfish
Takifugu rubipres
NP_001027889
115
12369
S91
L
S
K
H
L
G
I
S
P
N
R
I
Y
I
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18785
120
12823
P91
C
G
K
E
L
G
L
P
K
D
K
V
V
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
40
N.A.
89.5
90.4
N.A.
78.2
71.3
68.6
68.6
66
N.A.
N.A.
31.6
N.A.
Protein Similarity:
100
N.A.
N.A.
44.3
N.A.
95.6
95.6
N.A.
86
88.6
86
79.1
80.8
N.A.
N.A.
49.1
N.A.
P-Site Identity:
100
N.A.
N.A.
0
N.A.
80
80
N.A.
60
60
53.3
53.3
60
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
93.3
93.3
N.A.
66.6
80
73.3
73.3
86.6
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
0
0
0
0
40
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
70
0
0
10
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
40
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
40
0
30
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
60
0
0
0
0
20
0
90
0
% I
% Lys:
0
0
60
0
0
0
0
0
10
0
10
0
0
0
0
% K
% Leu:
70
0
0
0
90
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
20
0
0
0
20
10
0
0
0
80
% N
% Pro:
0
10
10
0
0
0
10
40
40
10
0
0
0
10
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
30
10
10
0
0
0
0
80
10
0
0
0
% R
% Ser:
0
30
0
10
0
0
0
60
0
0
0
0
0
0
0
% S
% Thr:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
20
0
0
0
0
70
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _