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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FDPS All Species: 9.09
Human Site: S34 Identified Species: 15.38
UniProt: P14324 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14324 NP_001129293.1 419 48275 S34 L G S L R R P S L V H G Y P V
Chimpanzee Pan troglodytes XP_513857 867 96008 S34 L G S L R R P S L V H G Y P V
Rhesus Macaque Macaca mulatta XP_001116071 419 48272 S34 L G S L R R P S L V H G Y P V
Dog Lupus familis XP_537252 420 48029 L35 G L H R R P S L V H G F P V L
Cat Felis silvestris
Mouse Mus musculus Q920E5 353 40563 D8 M N G N Q K L D A Y N Q E K Q
Rat Rattus norvegicus P05369 353 40811 D8 M N G D Q K L D V H N Q E K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P08836 367 42135 V22 A L R N L S P V V V E R E R E
Frog Xenopus laevis NP_001084626 348 40044
Zebra Danio Brachydanio rerio NP_001020642 356 40805 Q11 S S C S N G V Q K K M S D P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781908 619 71431 M122 Q R A S V T D M L R D L N W D
Poplar Tree Populus trichocarpa
Maize Zea mays P49353 350 39995
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q43315 342 39807
Baker's Yeast Sacchar. cerevisiae P08524 352 40465
Red Bread Mold Neurospora crassa Q92250 347 40260
Conservation
Percent
Protein Identity: 100 43 97.3 87.1 N.A. 71.1 71.3 N.A. N.A. 59.6 57 53.7 N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 46.9 98.5 94 N.A. 79.2 78.2 N.A. N.A. 73.9 69.6 66.8 N.A. N.A. N.A. N.A. 49.6
P-Site Identity: 100 100 100 6.6 N.A. 0 0 N.A. N.A. 13.3 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 26.6 33.3 N.A. N.A. 20 0 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. 40.3 N.A. 41 38.6 42.7
Protein Similarity: N.A. 55.3 N.A. 57.2 56.8 56.5
P-Site Identity: N.A. 0 N.A. 0 0 0
P-Site Similarity: N.A. 0 N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 8 15 0 0 8 0 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 22 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 22 15 0 0 8 0 0 0 0 8 22 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 15 22 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 15 0 0 8 8 0 0 0 15 0 % K
% Leu: 22 15 0 22 8 0 15 8 29 0 0 8 0 0 8 % L
% Met: 15 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % M
% Asn: 0 15 0 15 8 0 0 0 0 0 15 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 29 0 0 0 0 0 8 29 0 % P
% Gln: 8 0 0 0 15 0 0 8 0 0 0 15 0 0 22 % Q
% Arg: 0 8 8 8 29 22 0 0 0 8 0 8 0 8 0 % R
% Ser: 8 8 22 15 0 8 8 22 0 0 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 8 8 22 29 0 0 0 8 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 22 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _