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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDPS
All Species:
10
Human Site:
S73
Identified Species:
16.92
UniProt:
P14324
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14324
NP_001129293.1
419
48275
S73
R
M
N
G
D
Q
N
S
D
V
Y
A
Q
E
K
Chimpanzee
Pan troglodytes
XP_513857
867
96008
S73
R
M
N
G
D
Q
N
S
D
V
Y
A
Q
E
K
Rhesus Macaque
Macaca mulatta
XP_001116071
419
48272
S73
R
M
N
G
D
Q
K
S
D
V
Y
A
Q
E
K
Dog
Lupus familis
XP_537252
420
48029
L74
R
M
N
G
D
Q
K
L
D
A
Y
A
Q
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q920E5
353
40563
E47
D
A
I
A
R
L
K
E
V
L
E
Y
N
A
L
Rat
Rattus norvegicus
P05369
353
40811
E47
D
A
I
T
R
I
K
E
V
L
E
Y
N
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08836
367
42135
E61
D
A
V
A
R
L
K
E
V
L
Q
Y
N
A
P
Frog
Xenopus laevis
NP_001084626
348
40044
E42
D
A
I
G
R
L
K
E
V
L
Q
Y
N
T
L
Zebra Danio
Brachydanio rerio
NP_001020642
356
40805
E50
D
A
L
N
R
L
R
E
V
L
Q
Y
N
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781908
619
71431
A161
P
K
T
L
T
P
L
A
V
T
C
N
R
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49353
350
39995
D44
E
E
S
R
Q
W
I
D
R
M
V
D
Y
N
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q43315
342
39807
W34
F
T
H
E
S
R
Q
W
L
E
R
M
L
D
Y
Baker's Yeast
Sacchar. cerevisiae
P08524
352
40465
N45
D
W
Y
A
H
S
L
N
Y
N
T
P
G
G
K
Red Bread Mold
Neurospora crassa
Q92250
347
40260
S41
M
L
S
W
Y
K
Q
S
L
E
V
N
T
L
G
Conservation
Percent
Protein Identity:
100
43
97.3
87.1
N.A.
71.1
71.3
N.A.
N.A.
59.6
57
53.7
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
46.9
98.5
94
N.A.
79.2
78.2
N.A.
N.A.
73.9
69.6
66.8
N.A.
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
100
93.3
66.6
N.A.
0
0
N.A.
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
40.3
N.A.
41
38.6
42.7
Protein Similarity:
N.A.
55.3
N.A.
57.2
56.8
56.5
P-Site Identity:
N.A.
0
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
13.3
N.A.
20
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
0
22
0
0
0
8
0
8
0
29
0
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
43
0
0
0
29
0
0
8
29
0
0
8
0
8
0
% D
% Glu:
8
8
0
8
0
0
0
36
0
15
15
0
0
22
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
36
0
0
0
0
0
0
0
0
8
8
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
22
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
43
0
0
0
0
0
0
0
29
% K
% Leu:
0
8
8
8
0
29
15
8
15
36
0
0
8
8
15
% L
% Met:
8
29
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
29
8
0
0
15
8
0
8
0
15
36
8
0
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
15
% P
% Gln:
0
0
0
0
8
29
15
0
0
0
22
0
29
8
0
% Q
% Arg:
29
0
0
8
36
8
8
0
8
0
8
0
8
0
15
% R
% Ser:
0
0
15
0
8
8
0
29
0
0
0
0
0
0
0
% S
% Thr:
0
8
8
8
8
0
0
0
0
8
8
0
8
15
0
% T
% Val:
0
0
8
0
0
0
0
0
43
22
15
0
0
0
15
% V
% Trp:
0
8
0
8
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
8
0
29
36
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _