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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDPS
All Species:
13.33
Human Site:
Y124
Identified Species:
22.56
UniProt:
P14324
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14324
NP_001129293.1
419
48275
Y124
Y
N
A
I
G
G
K
Y
N
R
G
L
T
V
V
Chimpanzee
Pan troglodytes
XP_513857
867
96008
Y124
Y
N
A
I
G
G
K
Y
N
R
G
L
T
V
V
Rhesus Macaque
Macaca mulatta
XP_001116071
419
48272
Y124
Y
N
A
I
G
G
K
Y
H
R
G
L
T
V
V
Dog
Lupus familis
XP_537252
420
48029
Y125
Y
N
A
V
G
G
K
Y
Q
R
G
L
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q920E5
353
40563
C91
R
A
L
T
V
G
W
C
V
E
L
L
Q
A
F
Rat
Rattus norvegicus
P05369
353
40811
C91
R
A
L
T
V
G
W
C
V
E
L
L
Q
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08836
367
42135
C105
C
A
L
A
V
G
W
C
I
E
L
F
Q
A
F
Frog
Xenopus laevis
NP_001084626
348
40044
C86
R
A
L
A
V
G
W
C
V
E
L
L
Q
A
F
Zebra Danio
Brachydanio rerio
NP_001020642
356
40805
C94
R
A
L
L
V
G
W
C
I
E
L
L
Q
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781908
619
71431
R324
Y
T
V
P
G
G
K
R
N
R
G
L
T
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49353
350
39995
W88
F
L
A
C
T
L
G
W
C
I
E
W
L
Q
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q43315
342
39807
L78
E
T
F
L
S
C
A
L
G
W
C
I
E
W
L
Baker's Yeast
Sacchar. cerevisiae
P08524
352
40465
I89
V
A
I
L
G
W
C
I
E
L
L
Q
A
Y
F
Red Bread Mold
Neurospora crassa
Q92250
347
40260
E85
A
T
L
G
W
M
T
E
L
L
Q
A
F
F
L
Conservation
Percent
Protein Identity:
100
43
97.3
87.1
N.A.
71.1
71.3
N.A.
N.A.
59.6
57
53.7
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
46.9
98.5
94
N.A.
79.2
78.2
N.A.
N.A.
73.9
69.6
66.8
N.A.
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
100
93.3
80
N.A.
13.3
13.3
N.A.
N.A.
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
40.3
N.A.
41
38.6
42.7
Protein Similarity:
N.A.
55.3
N.A.
57.2
56.8
56.5
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
0
P-Site Similarity:
N.A.
20
N.A.
20
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
36
15
0
0
8
0
0
0
0
8
8
36
8
% A
% Cys:
8
0
0
8
0
8
8
36
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
8
36
8
0
8
0
0
% E
% Phe:
8
0
8
0
0
0
0
0
0
0
0
8
8
8
43
% F
% Gly:
0
0
0
8
43
72
8
0
8
0
36
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
22
0
0
0
8
15
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
43
22
0
8
0
8
8
15
43
65
8
0
22
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
29
0
0
0
0
0
0
22
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
8
36
8
0
% Q
% Arg:
29
0
0
0
0
0
0
8
0
36
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
22
0
15
8
0
8
0
0
0
0
0
36
0
0
% T
% Val:
8
0
8
8
36
0
0
0
22
0
0
0
0
36
29
% V
% Trp:
0
0
0
0
8
8
36
8
0
8
0
8
0
8
0
% W
% Tyr:
36
0
0
0
0
0
0
29
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _