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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDPS
All Species:
18.48
Human Site:
Y273
Identified Species:
31.28
UniProt:
P14324
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14324
NP_001129293.1
419
48275
Y273
K
T
A
F
Y
S
F
Y
L
P
I
A
A
A
M
Chimpanzee
Pan troglodytes
XP_513857
867
96008
Y273
K
T
A
F
Y
S
F
Y
L
P
I
A
A
A
M
Rhesus Macaque
Macaca mulatta
XP_001116071
419
48272
Y273
K
T
A
F
Y
S
F
Y
L
P
I
A
A
A
M
Dog
Lupus familis
XP_537252
420
48029
Y274
K
T
A
F
Y
S
F
Y
L
P
V
A
A
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q920E5
353
40563
H225
G
I
D
G
E
K
E
H
A
N
A
L
K
I
L
Rat
Rattus norvegicus
P05369
353
40811
H225
G
I
D
G
E
K
E
H
A
N
A
L
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08836
367
42135
H239
G
I
D
S
K
E
E
H
E
N
A
K
A
I
L
Frog
Xenopus laevis
NP_001084626
348
40044
H220
G
I
D
G
E
E
E
H
K
N
A
K
T
I
L
Zebra Danio
Brachydanio rerio
NP_001020642
356
40805
H228
G
I
E
N
E
I
E
H
H
N
A
K
T
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781908
619
71431
Y473
K
T
A
F
Y
S
F
Y
L
P
E
A
L
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49353
350
39995
Y222
S
G
E
N
L
D
N
Y
G
D
V
E
N
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q43315
342
39807
H214
A
G
E
N
L
E
N
H
T
D
V
K
T
V
L
Baker's Yeast
Sacchar. cerevisiae
P08524
352
40465
K223
I
T
D
E
K
D
L
K
Q
A
R
D
V
L
I
Red Bread Mold
Neurospora crassa
Q92250
347
40260
Q219
A
T
P
E
N
L
K
Q
A
E
D
I
L
I
P
Conservation
Percent
Protein Identity:
100
43
97.3
87.1
N.A.
71.1
71.3
N.A.
N.A.
59.6
57
53.7
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
46.9
98.5
94
N.A.
79.2
78.2
N.A.
N.A.
73.9
69.6
66.8
N.A.
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
N.A.
6.6
0
0
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
40.3
N.A.
41
38.6
42.7
Protein Similarity:
N.A.
55.3
N.A.
57.2
56.8
56.5
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
20
N.A.
20
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
36
0
0
0
0
0
22
8
36
36
36
36
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
36
0
0
15
0
0
0
15
8
8
0
0
0
% D
% Glu:
0
0
22
15
29
22
36
0
8
8
8
8
0
0
0
% E
% Phe:
0
0
0
36
0
0
36
0
0
0
0
0
0
0
0
% F
% Gly:
36
15
0
22
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
43
8
0
0
0
0
0
0
% H
% Ile:
8
36
0
0
0
8
0
0
0
0
22
8
0
50
8
% I
% Lys:
36
0
0
0
15
15
8
8
8
0
0
29
15
0
0
% K
% Leu:
0
0
0
0
15
8
8
0
36
0
0
15
15
8
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% M
% Asn:
0
0
0
22
8
0
15
0
0
36
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
36
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
8
0
36
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
50
0
0
0
0
0
0
8
0
0
0
22
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
22
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
36
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _