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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDPS
All Species:
11.21
Human Site:
Y388
Identified Species:
18.97
UniProt:
P14324
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14324
NP_001129293.1
419
48275
Y388
L
Q
Y
E
E
D
S
Y
S
H
I
M
A
L
I
Chimpanzee
Pan troglodytes
XP_513857
867
96008
Q439
R
L
W
M
A
E
A
Q
S
G
T
G
Q
L
Q
Rhesus Macaque
Macaca mulatta
XP_001116071
419
48272
Y388
L
Q
Y
E
E
D
S
Y
S
H
I
M
A
L
I
Dog
Lupus familis
XP_537252
420
48029
Y389
T
Q
Y
E
E
D
S
Y
S
R
L
M
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q920E5
353
40563
L325
E
E
D
S
Y
N
R
L
K
S
L
I
E
Q
C
Rat
Rattus norvegicus
P05369
353
40811
L325
E
E
D
S
Y
N
R
L
K
S
L
I
E
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08836
367
42135
L339
E
E
S
S
Y
R
R
L
Q
E
L
I
E
K
H
Frog
Xenopus laevis
NP_001084626
348
40044
L320
E
E
E
S
Y
Q
R
L
Q
L
L
I
S
Q
H
Zebra Danio
Brachydanio rerio
NP_001020642
356
40805
L328
E
E
E
S
Y
H
R
L
Q
K
L
I
Q
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781908
619
71431
Y588
R
S
Y
E
E
S
S
Y
N
D
L
M
D
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49353
350
39995
L322
E
N
E
S
Y
K
K
L
I
A
D
I
E
A
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q43315
342
39807
L314
E
K
E
S
Y
E
K
L
T
K
L
I
E
A
H
Baker's Yeast
Sacchar. cerevisiae
P08524
352
40465
K323
E
S
I
A
K
D
L
K
A
K
I
S
Q
V
D
Red Bread Mold
Neurospora crassa
Q92250
347
40260
K319
E
R
V
G
E
I
R
K
M
I
D
A
I
D
E
Conservation
Percent
Protein Identity:
100
43
97.3
87.1
N.A.
71.1
71.3
N.A.
N.A.
59.6
57
53.7
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
46.9
98.5
94
N.A.
79.2
78.2
N.A.
N.A.
73.9
69.6
66.8
N.A.
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
13.3
100
73.3
N.A.
0
0
N.A.
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
33.3
100
86.6
N.A.
26.6
26.6
N.A.
N.A.
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
40.3
N.A.
41
38.6
42.7
Protein Similarity:
N.A.
55.3
N.A.
57.2
56.8
56.5
P-Site Identity:
N.A.
0
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
6.6
N.A.
33.3
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
8
8
0
8
15
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
15
0
0
29
0
0
0
8
15
0
8
8
8
% D
% Glu:
65
36
29
29
36
15
0
0
0
8
0
0
36
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
15
0
0
0
0
29
% H
% Ile:
0
0
8
0
0
8
0
0
8
8
22
50
8
0
29
% I
% Lys:
0
8
0
0
8
8
15
15
15
22
0
0
0
8
0
% K
% Leu:
15
8
0
0
0
0
8
50
0
8
58
0
0
36
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
29
0
0
0
% M
% Asn:
0
8
0
0
0
15
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
22
0
0
0
8
0
8
22
0
0
0
22
22
15
% Q
% Arg:
15
8
0
0
0
8
43
0
0
8
0
0
0
0
0
% R
% Ser:
0
15
8
50
0
8
29
0
29
15
0
8
15
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
29
0
50
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _