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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 18.48
Human Site: S1449 Identified Species: 40.67
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 S1449 Q I L S D G T S V L H Y D V H
Chimpanzee Pan troglodytes XP_526371 1826 209197 S1448 Q I L S D G T S V L H Y D V H
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 P1474 Q I L P D G S P V Q H Y N V H
Dog Lupus familis XP_545265 1886 215728 S1509 Q I L S D G S S V L H Y N V H
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 S1440 H I L S D G S S V L H Y D V H
Rat Rattus norvegicus P23739 1841 210332 S1461 H I L I D G S S V L Q Y D V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 F220 E P H K S L K F D G L W I D M
Chicken Gallus gallus XP_422811 1809 205701 P1432 Q Y L P D G T P V R H Y D V H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 G951 Y D V H N L Y G L S H T K P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 M540 H S L Y G H A M S E M S F V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 T549 P F I L S R S T F V G S G Q Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 66.6 86.6 N.A. 86.6 73.3 N.A. 0 73.3 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 80 100 N.A. 93.3 80 N.A. 13.3 73.3 N.A. 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 64 0 0 0 10 0 0 0 46 10 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 10 10 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 10 64 0 10 0 10 10 0 10 0 0 % G
% His: 28 0 10 10 0 10 0 0 0 0 64 0 0 0 64 % H
% Ile: 0 55 10 10 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 10 0 0 10 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 73 10 0 19 0 0 10 46 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 19 0 0 % N
% Pro: 10 10 0 19 0 0 0 19 0 0 0 0 0 10 0 % P
% Gln: 46 0 0 0 0 0 0 0 0 10 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 10 0 37 19 0 46 46 10 10 0 19 0 0 0 % S
% Thr: 0 0 0 0 0 0 28 10 0 0 0 10 0 0 19 % T
% Val: 0 0 10 0 0 0 0 0 64 10 0 0 0 73 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 10 10 0 10 0 0 10 0 0 0 0 64 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _