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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 11.21
Human Site: S984 Identified Species: 24.67
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 S984 P R Q D N S Y S V N S A R Y S
Chimpanzee Pan troglodytes XP_526371 1826 209197 S983 P R Q D N S Y S V N S A R Y S
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 S1013 Y F V N D L Y S V S N V Q Y S
Dog Lupus familis XP_545265 1886 215728 L1044 P R Q S N P Y L V R S T Q Y S
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 L975 P S N H N P Y L L T S T Q K L
Rat Rattus norvegicus P23739 1841 210332 T990 P P E N N P Y T L T S I Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593
Chicken Gallus gallus XP_422811 1809 205701 V963 S S D N V Y S V G E V E Y S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 N503 R S Q S P D I N K L R V E I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 Y92 H P N G D Y G Y A M I S E P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 R101 V P Y N L L P R E Q P P Q V G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 33.3 60 N.A. 26.6 26.6 N.A. 0 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 66.6 66.6 N.A. 40 60 N.A. 0 13.3 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 19 19 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 10 10 0 10 19 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 10 0 10 0 0 0 0 0 10 % G
% His: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 10 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 10 19 0 19 19 10 0 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 19 37 46 0 0 10 0 19 10 0 0 0 0 % N
% Pro: 46 28 0 0 10 28 10 0 0 0 10 10 0 19 0 % P
% Gln: 0 0 37 0 0 0 0 0 0 10 0 0 46 0 0 % Q
% Arg: 10 28 0 0 0 0 0 10 0 10 10 0 19 0 0 % R
% Ser: 10 28 0 19 0 19 10 28 0 10 46 10 0 10 46 % S
% Thr: 0 0 0 0 0 0 0 10 0 19 0 19 0 0 19 % T
% Val: 10 0 10 0 10 0 0 10 37 0 10 19 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 19 55 10 0 0 0 0 10 37 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _