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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 21.21
Human Site: T1346 Identified Species: 46.67
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 T1346 P N I T I D K T L T E D E A V
Chimpanzee Pan troglodytes XP_526371 1826 209197 T1345 P N I T I D K T L T E D E A V
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 V1372 P D F P G V V V N D S L D W D
Dog Lupus familis XP_545265 1886 215728 S1406 P N I T I D E S L T E D E A V
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 T1337 P N I T I D E T I T E D E A V
Rat Rattus norvegicus P23739 1841 210332 T1351 P N V T I D E T I T E D E A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 I119 K T A G M R V I L I L D P A I
Chicken Gallus gallus XP_422811 1809 205701 S1324 P N V Q V N E S L P E Q T Q I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 V850 V E L F R S F V A F P D F F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 P439 P I V G R V W P N E S V Y P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 C448 M N E V S N F C S G L C T I P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 6.6 86.6 N.A. 86.6 80 N.A. 20 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 33.3 66.6 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 10 0 0 0 0 55 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 0 10 0 0 0 46 0 0 0 10 0 64 10 0 19 % D
% Glu: 0 10 10 0 0 0 37 0 0 10 55 0 46 0 0 % E
% Phe: 0 0 10 10 0 0 19 0 0 10 0 0 10 10 0 % F
% Gly: 0 0 0 19 10 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 37 0 46 0 0 10 19 10 0 0 0 10 19 % I
% Lys: 10 0 0 0 0 0 19 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 10 0 0 0 0 0 46 0 19 10 0 0 0 % L
% Met: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 64 0 0 0 19 0 0 19 0 0 0 0 0 0 % N
% Pro: 73 0 0 10 0 0 0 10 0 10 10 0 10 10 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 10 0 10 0 % Q
% Arg: 0 0 0 0 19 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 19 10 0 19 0 0 0 0 % S
% Thr: 0 10 0 46 0 0 0 37 0 46 0 0 19 0 0 % T
% Val: 10 0 28 10 10 19 19 19 0 0 0 10 0 0 46 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _