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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 5.45
Human Site: T1767 Identified Species: 12
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 T1767 G Y I N K S E T R L G S L H V
Chimpanzee Pan troglodytes XP_526371 1826 209197 T1766 G Y I N K S E T R L G S V H V
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 L1155 H T S Y R R D L E W H T W G M
Dog Lupus familis XP_545265 1886 215728 M1826 G Y I N K D E M R L G F I I I
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 M1758 G Y R N K S E M K L G S I Y V
Rat Rattus norvegicus P23739 1841 210332 M1781 G Y K N K Q E M R L G S I H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 P527 H I L P C Q E P A N N T H F R
Chicken Gallus gallus XP_422811 1809 205701 L1750 G Y S D P N N L M F T E I K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 L1258 L E E A D R P L L G E V K V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 Y847 Y T D P N S L Y F A D I S I Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 S856 L R G A G Q V S E I Q I N G S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 93.3 0 60 N.A. 66.6 66.6 N.A. 6.6 20 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 26.6 73.3 N.A. 86.6 80 N.A. 20 40 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 0 0 10 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 10 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 10 10 0 0 0 55 0 19 0 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 10 0 10 0 10 0 % F
% Gly: 55 0 10 0 10 0 0 0 0 10 46 0 0 19 0 % G
% His: 19 0 0 0 0 0 0 0 0 0 10 0 10 28 0 % H
% Ile: 0 10 28 0 0 0 0 0 0 10 0 19 37 19 19 % I
% Lys: 0 0 10 0 46 0 0 0 10 0 0 0 10 10 0 % K
% Leu: 19 0 10 0 0 0 10 28 10 46 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 28 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 46 10 10 10 0 0 10 10 0 10 0 0 % N
% Pro: 0 0 0 19 10 0 10 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 28 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 10 10 0 10 19 0 0 37 0 0 0 0 0 10 % R
% Ser: 0 0 19 0 0 37 0 10 0 0 0 37 10 0 10 % S
% Thr: 0 19 0 0 0 0 0 19 0 0 10 19 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 10 10 10 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % W
% Tyr: 10 55 0 10 0 0 0 10 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _