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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 26.97
Human Site: Y1110 Identified Species: 59.33
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 Y1110 S T R L P S E Y I Y G F G E V
Chimpanzee Pan troglodytes XP_526371 1826 209197 Y1109 S T R L P S E Y I Y G F G E V
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 Y1139 S T R L A S K Y L Y G F G E T
Dog Lupus familis XP_545265 1886 215728 Y1170 S T R L P S E Y I Y G F G E V
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 Y1101 S T R L P S Q Y L Y G F G E A
Rat Rattus norvegicus P23739 1841 210332 Y1115 S T R L P S N Y L Y G F G E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593
Chicken Gallus gallus XP_422811 1809 205701 Y1089 S T R L P S Q Y I Y G F G E T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 G627 F A K D Q P P G Y K L N S Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 Y216 Y L P S S N L Y G F G E H N H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 N225 P M Y M D L R N V G G K A Y A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 73.3 100 N.A. 80 86.6 N.A. 0 86.6 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 86.6 100 N.A. 93.3 93.3 N.A. 0 93.3 N.A. 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 0 0 0 0 0 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 28 0 0 0 0 10 0 64 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 10 0 64 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 10 10 82 0 64 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 10 0 10 0 0 0 % K
% Leu: 0 10 0 64 0 10 10 0 28 0 10 0 0 0 0 % L
% Met: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 10 0 0 0 10 0 10 0 % N
% Pro: 10 0 10 0 55 10 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 19 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 64 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 64 0 0 10 10 64 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 19 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 0 73 10 64 0 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _