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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 25.15
Human Site: Y1231 Identified Species: 55.33
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 Y1231 L G F Q L C R Y G Y A N T S E
Chimpanzee Pan troglodytes XP_526371 1826 209197 Y1230 L G F Q L C R Y G Y A N T S E
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 Y1260 L G F Q L C R Y G Y Q N D S E
Dog Lupus familis XP_545265 1886 215728 Y1291 L G F Q I C R Y G Y R N T S Q
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 Y1222 L G F Q L C R Y G Y R N T S E
Rat Rattus norvegicus P23739 1841 210332 Y1236 L G F Q L C R Y G Y R N T S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 G15 A L T Y R T T G G I L D F F V
Chicken Gallus gallus XP_422811 1809 205701 Y1210 L G F Q L C R Y G Y R N D S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 I746 Y D V Q Y A D I D Y M E R Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 W335 L G F Q L S R W N Y G S L E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 A344 D F T L N P V A Y P R A K L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 86.6 80 N.A. 93.3 93.3 N.A. 6.6 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 86.6 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 10 0 0 19 10 0 0 0 % A
% Cys: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 10 0 10 0 0 10 19 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 55 % E
% Phe: 0 10 73 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 0 73 0 0 0 0 0 10 73 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 73 10 0 10 64 0 0 0 0 0 10 0 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 0 64 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 82 0 0 0 0 0 0 10 0 0 10 10 % Q
% Arg: 0 0 0 0 10 0 73 0 0 0 46 0 10 0 10 % R
% Ser: 0 0 0 0 0 10 0 0 0 0 0 10 0 64 0 % S
% Thr: 0 0 19 0 0 10 10 0 0 0 0 0 46 0 0 % T
% Val: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 10 0 0 64 10 82 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _