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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 17.27
Human Site: Y1554 Identified Species: 38
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 Y1554 Q L G A F Y P Y S R N H N I A
Chimpanzee Pan troglodytes XP_526371 1826 209197 Y1553 Q L G A F Y P Y S R N H N I A
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 F1579 Q L G A F Y P F S R N H N T I
Dog Lupus familis XP_545265 1886 215728 Y1614 Q L G A F Y P Y S R N H N I A
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 Y1545 Q V G A F Y P Y S R N H N I Q
Rat Rattus norvegicus P23739 1841 210332 P1566 I Q V G A F Y P Y P R E S P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 G325 F P S A G R W G G H W L G D N
Chicken Gallus gallus XP_422811 1809 205701 Y1537 Q L G S F Y P Y S R N H N E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 R1056 H N T I N M P R Q D P V A W G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 H645 G D G M I P Q H P T A F S T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 F654 M R Y K I L P F L Y T L N Y E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 80 100 N.A. 86.6 0 N.A. 6.6 80 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 100 N.A. 93.3 13.3 N.A. 6.6 86.6 N.A. 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 55 10 0 0 0 0 0 10 0 10 0 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 10 % E
% Phe: 10 0 0 0 55 10 0 19 0 0 0 10 0 0 0 % F
% Gly: 10 0 64 10 10 0 0 10 10 0 0 0 10 0 19 % G
% His: 10 0 0 0 0 0 0 10 0 10 0 55 0 0 0 % H
% Ile: 10 0 0 10 19 0 0 0 0 0 0 0 0 37 10 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 46 0 0 0 10 0 0 10 0 0 19 0 0 0 % L
% Met: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 55 0 64 0 10 % N
% Pro: 0 10 0 0 0 10 73 10 10 10 10 0 0 10 0 % P
% Gln: 55 10 0 0 0 0 10 0 10 0 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 10 0 10 0 55 10 0 0 0 0 % R
% Ser: 0 0 10 10 0 0 0 0 55 0 0 0 19 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 10 0 0 19 10 % T
% Val: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 10 0 0 10 0 % W
% Tyr: 0 0 10 0 0 55 10 46 10 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _