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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 23.94
Human Site: Y1659 Identified Species: 52.67
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 Y1659 P N A R W F D Y H T G K D I G
Chimpanzee Pan troglodytes XP_526371 1826 209197 Y1658 P N A R W F D Y H T G K D I G
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 Y1684 P R A R W Y D Y Y T G V D I D
Dog Lupus familis XP_545265 1886 215728 Y1719 P D A R W F D Y H T G Q D I G
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 Y1650 P K A R W F D Y H T G E D I K
Rat Rattus norvegicus P23739 1841 210332 Y1673 P K A R W F D Y H T G A D I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593 H429 P Y L Y T L M H D A H V T G N
Chicken Gallus gallus XP_422811 1809 205701 Y1642 P N A R W Y D Y H T D E H I N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 G1160 N E V V E G Q G Q F V D M D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358 K749 E M T E Q R G K L A Q L E A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 Q758 Q N T I L P T Q Q G G L I S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 66.6 86.6 N.A. 80 80 N.A. 6.6 66.6 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 80 100 N.A. 86.6 80 N.A. 13.3 80 N.A. 0 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 64 0 0 0 0 0 0 19 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 64 0 10 0 10 10 55 10 10 % D
% Glu: 10 10 0 10 10 0 0 0 0 0 0 19 10 0 0 % E
% Phe: 0 0 0 0 0 46 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 10 0 10 64 0 0 10 28 % G
% His: 0 0 0 0 0 0 0 10 55 0 10 0 10 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 10 64 0 % I
% Lys: 0 19 0 0 0 0 0 10 0 0 0 19 0 0 28 % K
% Leu: 0 0 10 0 10 10 0 0 10 0 0 19 0 0 0 % L
% Met: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 0 % M
% Asn: 10 37 0 0 0 0 0 0 0 0 0 0 0 0 19 % N
% Pro: 73 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 10 0 0 0 10 0 10 10 19 0 10 10 0 0 0 % Q
% Arg: 0 10 0 64 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 19 0 10 0 10 0 0 64 0 0 10 0 10 % T
% Val: 0 0 10 10 0 0 0 0 0 0 10 19 0 0 0 % V
% Trp: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 0 19 0 64 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _