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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SI All Species: 25.45
Human Site: Y763 Identified Species: 56
UniProt: P14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14410 NP_001032.2 1827 209405 Y763 Y I P D A I W Y D Y E S G A K
Chimpanzee Pan troglodytes XP_526371 1826 209197 Y762 Y I P D A I W Y D Y E S G A K
Rhesus Macaque Macaca mulatta XP_001083672 2150 242962 Y796 Y V P D A V W Y D Y E T G N Q
Dog Lupus familis XP_545265 1886 215728 Y824 Y I P N A T W Y D Y E T G A K
Cat Felis silvestris
Mouse Mus musculus NP_001074606 1818 208966 Y753 Y I P D A T W Y D Y E T G E K
Rat Rattus norvegicus P23739 1841 210332 Y769 Y I P N A T W Y D Y E T G I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519457 586 66593
Chicken Gallus gallus XP_422811 1809 205701 Y744 Y I P D A V W Y E Y E T G A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919135 1317 150404 L286 D D K L G L H L R G G A I L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792875 906 103358
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 50.1 81.7 N.A. 77.8 74.4 N.A. 20.8 61.1 N.A. 41.3 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.6 64.6 88.3 N.A. 87.3 84.6 N.A. 26 75.1 N.A. 52.9 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 66.6 80 N.A. 80 73.3 N.A. 0 73.3 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 0 100 N.A. 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 64 0 0 0 0 0 0 10 0 37 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 46 0 0 0 0 55 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 64 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 10 10 0 64 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 55 0 0 0 19 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 46 % K
% Leu: 0 0 0 10 0 10 0 10 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 64 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % S
% Thr: 0 0 0 0 0 28 0 0 0 0 0 46 0 0 0 % T
% Val: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 % W
% Tyr: 64 0 0 0 0 0 0 64 0 64 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _