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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DRD2 All Species: 14.24
Human Site: S229 Identified Species: 31.33
UniProt: P14416 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14416 NP_000786.1 443 50619 S229 R V N T K R S S R A F R A H L
Chimpanzee Pan troglodytes Q5IS72 400 44218 Q217 R I Y M V L K Q R R R K R I L
Rhesus Macaque Macaca mulatta XP_001085449 443 50600 S229 R V N T K R S S R A F R S H L
Dog Lupus familis XP_545106 447 49572 N228 K R I L T R Q N S Q C I S V R
Cat Felis silvestris
Mouse Mus musculus P30728 446 49651 N228 K R I L T R Q N S Q C I S I R
Rat Rattus norvegicus P61169 444 50885 S229 R V N T K R S S R A F R A N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106761 437 49525 S226 R V T T K R S S H V L D S D T
Frog Xenopus laevis P24628 442 49720 S223 R V N T K R N S R G V A V D A
Zebra Danio Brachydanio rerio Q90WY6 432 49119 R224 I Y Q V A K T R T R N M S E K
Tiger Blowfish Takifugu rubipres P53453 463 52101 Q230 R V N T K P K Q R L C Q A A D
Fruit Fly Dros. melanogaster Q8IS44 506 56459 P273 K Q R A A R K P H L S E L T G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.1 99.3 50.3 N.A. 50.2 95.7 N.A. N.A. 80.1 76 35.2 66.7 32.4 N.A. N.A. N.A.
Protein Similarity: 100 62.9 100 64.2 N.A. 63.9 98.1 N.A. N.A. 87.5 86 56.6 76.6 48 N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 6.6 N.A. 6.6 93.3 N.A. N.A. 46.6 53.3 0 46.6 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 26.6 100 N.A. N.A. 53.3 60 20 53.3 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 19 0 0 0 0 28 0 10 28 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 19 0 0 0 0 19 0 % H
% Ile: 10 10 19 0 0 0 0 0 0 0 0 19 0 19 0 % I
% Lys: 28 0 0 0 55 10 28 0 0 0 0 10 0 0 10 % K
% Leu: 0 0 0 19 0 10 0 0 0 19 10 0 10 0 37 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 46 0 0 0 10 19 0 0 10 0 0 10 0 % N
% Pro: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 10 10 0 0 0 19 19 0 19 0 10 0 0 0 % Q
% Arg: 64 19 10 0 0 73 0 10 55 19 10 28 10 0 19 % R
% Ser: 0 0 0 0 0 0 37 46 19 0 10 0 46 0 0 % S
% Thr: 0 0 10 55 19 0 10 0 10 0 0 0 0 10 10 % T
% Val: 0 55 0 10 10 0 0 0 0 10 10 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _