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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD2
All Species:
21.21
Human Site:
T254
Identified Species:
46.67
UniProt:
P14416
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14416
NP_000786.1
443
50619
T254
P
E
D
M
K
L
C
T
V
I
M
K
S
N
G
Chimpanzee
Pan troglodytes
Q5IS72
400
44218
Q241
V
R
P
G
F
P
Q
Q
T
L
S
P
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001085449
443
50600
T254
P
E
D
M
K
L
C
T
V
I
M
K
S
N
G
Dog
Lupus familis
XP_545106
447
49572
S254
L
H
P
I
R
Q
F
S
I
R
D
R
F
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P30728
446
49651
F259
Q
F
S
I
R
A
R
F
L
S
D
A
T
G
Q
Rat
Rattus norvegicus
P61169
444
50885
T254
P
E
D
M
K
L
C
T
V
I
M
K
S
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106761
437
49525
T251
P
E
D
V
K
L
C
T
V
I
V
K
S
N
G
Frog
Xenopus laevis
P24628
442
49720
V248
V
K
L
C
S
V
F
V
K
S
N
G
S
F
P
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
R250
R
L
E
N
G
L
S
R
E
D
S
R
R
E
N
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
T258
P
E
D
V
R
L
C
T
M
I
V
K
S
N
G
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
S305
L
D
S
S
R
H
A
S
R
I
L
P
D
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
99.3
50.3
N.A.
50.2
95.7
N.A.
N.A.
80.1
76
35.2
66.7
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
62.9
100
64.2
N.A.
63.9
98.1
N.A.
N.A.
87.5
86
56.6
76.6
48
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
100
N.A.
N.A.
86.6
6.6
6.6
73.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
33.3
N.A.
26.6
100
N.A.
N.A.
100
20
20
100
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
19
% A
% Cys:
0
0
0
10
0
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
46
0
0
0
0
0
0
10
19
0
19
0
0
% D
% Glu:
0
46
10
0
0
0
0
0
10
0
0
0
0
19
0
% E
% Phe:
0
10
0
0
10
0
19
10
0
0
0
0
10
10
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
0
0
10
0
10
46
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
0
0
0
10
55
0
0
0
0
0
% I
% Lys:
0
10
0
0
37
0
0
0
10
0
0
46
0
0
0
% K
% Leu:
19
10
10
0
0
55
0
0
10
10
10
0
0
0
0
% L
% Met:
0
0
0
28
0
0
0
0
10
0
28
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
0
0
46
10
% N
% Pro:
46
0
19
0
0
10
0
0
0
0
0
19
0
19
10
% P
% Gln:
10
0
0
0
0
10
10
10
0
0
0
0
0
0
10
% Q
% Arg:
10
10
0
0
37
0
10
10
10
10
0
19
10
0
0
% R
% Ser:
0
0
19
10
10
0
10
19
0
19
19
0
55
0
10
% S
% Thr:
0
0
0
0
0
0
0
46
10
0
0
0
10
0
0
% T
% Val:
19
0
0
19
0
10
0
10
37
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _