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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD2
All Species:
31.82
Human Site:
T428
Identified Species:
70
UniProt:
P14416
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14416
NP_000786.1
443
50619
T428
V
N
P
I
I
Y
T
T
F
N
I
E
F
R
K
Chimpanzee
Pan troglodytes
Q5IS72
400
44218
K392
T
F
N
I
E
F
R
K
A
F
L
K
I
L
S
Rhesus Macaque
Macaca mulatta
XP_001085449
443
50600
T428
V
N
P
I
I
Y
T
T
F
N
I
E
F
R
K
Dog
Lupus familis
XP_545106
447
49572
T432
L
N
P
V
I
Y
T
T
F
N
V
E
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P30728
446
49651
T431
L
N
P
V
I
Y
T
T
F
N
I
E
F
R
K
Rat
Rattus norvegicus
P61169
444
50885
T429
V
N
P
I
I
Y
T
T
F
N
I
E
F
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106761
437
49525
T422
V
N
P
I
I
Y
T
T
F
N
I
E
F
R
K
Frog
Xenopus laevis
P24628
442
49720
T427
V
N
P
I
I
Y
T
T
F
N
V
E
F
R
K
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
I411
L
N
P
V
I
Y
T
I
F
N
Q
D
F
R
R
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
T448
V
N
P
I
I
Y
T
T
F
N
V
E
F
R
K
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
I490
V
N
P
V
I
Y
T
I
F
N
P
E
F
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
99.3
50.3
N.A.
50.2
95.7
N.A.
N.A.
80.1
76
35.2
66.7
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
62.9
100
64.2
N.A.
63.9
98.1
N.A.
N.A.
87.5
86
56.6
76.6
48
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
86.6
100
N.A.
N.A.
100
93.3
60
93.3
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
100
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
82
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
91
10
0
0
91
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
64
91
0
0
19
0
0
46
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
82
% K
% Leu:
28
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
91
10
0
0
0
0
0
0
91
0
0
0
0
0
% N
% Pro:
0
0
91
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
91
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
91
73
0
0
0
0
0
0
0
% T
% Val:
64
0
0
37
0
0
0
0
0
0
28
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _