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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1A1
All Species:
36.36
Human Site:
T208
Identified Species:
80
UniProt:
P14550
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14550
NP_006057.1
325
36573
T208
Q
A
R
G
L
E
V
T
A
Y
S
P
L
G
S
Chimpanzee
Pan troglodytes
XP_001157388
325
36541
T208
Q
A
R
G
L
E
V
T
A
Y
S
P
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001082982
325
36613
T208
Q
A
R
G
L
E
V
T
A
Y
S
P
L
G
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII6
325
36568
T208
H
A
R
G
L
E
V
T
A
Y
S
P
L
G
S
Rat
Rattus norvegicus
P51635
325
36487
T208
Q
A
R
G
L
E
V
T
A
Y
S
P
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507980
327
36885
I210
R
E
R
G
L
E
V
I
A
Y
S
P
L
G
S
Chicken
Gallus gallus
Q5ZK84
327
37058
T210
Q
K
R
G
L
V
V
T
A
Y
S
P
L
G
S
Frog
Xenopus laevis
Q6GMC7
327
37081
T210
R
S
H
G
L
V
L
T
G
Y
S
P
L
G
S
Zebra Danio
Brachydanio rerio
Q568L5
324
36800
T207
R
D
R
G
L
V
M
T
A
Y
S
P
L
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624353
318
36064
T210
K
D
K
D
I
L
I
T
A
Y
S
P
L
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792112
333
37321
S208
R
E
R
S
V
V
V
S
A
Y
S
P
L
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
N.A.
N.A.
93.2
94.1
N.A.
82.2
77.9
73
71
N.A.
N.A.
49.2
N.A.
47.4
Protein Similarity:
100
100
99.6
N.A.
N.A.
96.6
97.8
N.A.
91.7
87.7
86.5
83
N.A.
N.A.
70.7
N.A.
65.7
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
80
86.6
60
73.3
N.A.
N.A.
53.3
N.A.
53.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
86.6
86.6
80
86.6
N.A.
N.A.
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
0
0
91
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
0
0
55
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
82
0
0
0
0
10
0
0
0
0
100
0
% G
% His:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
82
10
10
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
37
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
10
0
0
0
10
0
0
100
0
0
0
91
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
37
73
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _