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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1A1
All Species:
38.96
Human Site:
Y319
Identified Species:
85.71
UniProt:
P14550
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14550
NP_006057.1
325
36573
Y319
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Chimpanzee
Pan troglodytes
XP_001157388
325
36541
Y319
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Rhesus Macaque
Macaca mulatta
XP_001082982
325
36613
Y319
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII6
325
36568
Y319
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Rat
Rattus norvegicus
P51635
325
36487
Y319
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507980
327
36885
Y321
R
D
A
G
H
P
F
Y
P
F
N
D
P
Y
_
Chicken
Gallus gallus
Q5ZK84
327
37058
Y321
R
D
A
G
H
P
N
Y
P
F
N
D
P
Y
_
Frog
Xenopus laevis
Q6GMC7
327
37081
Y321
R
D
A
G
H
P
L
Y
P
F
N
D
P
Y
_
Zebra Danio
Brachydanio rerio
Q568L5
324
36800
Y318
R
D
A
G
H
P
H
Y
P
F
N
D
P
Y
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624353
318
36064
P310
L
S
G
S
E
A
S
P
H
Y
P
F
H
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792112
333
37321
Y327
R
D
G
S
H
P
Y
Y
P
F
H
E
P
F
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
N.A.
N.A.
93.2
94.1
N.A.
82.2
77.9
73
71
N.A.
N.A.
49.2
N.A.
47.4
Protein Similarity:
100
100
99.6
N.A.
N.A.
96.6
97.8
N.A.
91.7
87.7
86.5
83
N.A.
N.A.
70.7
N.A.
65.7
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
92.8
92.8
100
92.8
N.A.
N.A.
0
N.A.
57.1
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
92.8
92.8
100
92.8
N.A.
N.A.
6.6
N.A.
78.5
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
82
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
91
0
0
0
0
0
0
0
0
0
82
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
91
0
10
0
10
0
% F
% Gly:
0
0
19
82
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
91
0
10
0
10
0
10
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
82
0
0
0
0
% N
% Pro:
0
0
0
0
0
91
0
10
91
0
10
0
91
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
19
0
0
10
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
91
0
10
0
0
0
82
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
91
% _