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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1A1
All Species:
33.33
Human Site:
Y50
Identified Species:
73.33
UniProt:
P14550
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14550
NP_006057.1
325
36573
Y50
H
I
D
C
A
A
I
Y
G
N
E
P
E
I
G
Chimpanzee
Pan troglodytes
XP_001157388
325
36541
Y50
H
I
D
C
A
A
I
Y
G
N
E
P
E
I
G
Rhesus Macaque
Macaca mulatta
XP_001082982
325
36613
Y50
H
I
D
C
A
A
I
Y
G
N
E
P
E
I
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII6
325
36568
Y50
H
I
D
C
A
S
V
Y
G
N
E
T
E
I
G
Rat
Rattus norvegicus
P51635
325
36487
Y50
H
I
D
C
A
S
V
Y
G
N
E
T
E
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507980
327
36885
Y52
H
I
D
C
A
A
I
Y
G
N
E
V
E
I
G
Chicken
Gallus gallus
Q5ZK84
327
37058
Y52
H
V
D
C
A
A
A
Y
S
N
E
A
E
I
G
Frog
Xenopus laevis
Q6GMC7
327
37081
Y52
H
I
D
C
A
F
V
Y
G
N
E
T
E
V
G
Zebra Danio
Brachydanio rerio
Q568L5
324
36800
E57
A
N
E
P
E
I
G
E
A
F
Q
E
T
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624353
318
36064
Y53
H
I
D
C
A
H
V
Y
G
N
E
K
E
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792112
333
37321
R60
K
E
V
G
V
A
L
R
E
A
M
Q
R
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
N.A.
N.A.
93.2
94.1
N.A.
82.2
77.9
73
71
N.A.
N.A.
49.2
N.A.
47.4
Protein Similarity:
100
100
99.6
N.A.
N.A.
96.6
97.8
N.A.
91.7
87.7
86.5
83
N.A.
N.A.
70.7
N.A.
65.7
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
93.3
73.3
73.3
6.6
N.A.
N.A.
73.3
N.A.
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
80
86.6
26.6
N.A.
N.A.
86.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
82
55
10
0
10
10
0
10
0
0
0
% A
% Cys:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
10
0
0
10
10
0
82
10
82
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
73
0
0
0
0
0
100
% G
% His:
82
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
0
0
10
37
0
0
0
0
0
0
64
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
82
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
28
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
28
10
0
0
% T
% Val:
0
10
10
0
10
0
37
0
0
0
0
10
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _