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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNB1 All Species: 17.88
Human Site: S35 Identified Species: 32.78
UniProt: P14635 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14635 NP_114172.1 433 48337 S35 P T A P A A T S K P G L R P R
Chimpanzee Pan troglodytes XP_517728 536 59103 S138 P T A P A A T S K P G L R P R
Rhesus Macaque Macaca mulatta XP_001091533 433 48375 S35 P T A P A A T S K P G L R P R
Dog Lupus familis XP_850398 425 47378 S35 P L A S A A A S K P G L R P R
Cat Felis silvestris
Mouse Mus musculus P24860 430 48033 S35 P V T V T A A S K P G L R P R
Rat Rattus norvegicus P30277 423 47373 S34 V P V A V A A S K P L L R S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507609 428 47366 A34 A P G P S A A A K Q A P R P R
Chicken Gallus gallus P29332 399 44633 G30 K A K V Q V T G K R A V L E E
Frog Xenopus laevis P13350 397 44655 K30 G K R V V A T K P G L R P R T
Zebra Danio Brachydanio rerio NP_571588 398 44818 L33 V V A N K P G L R P R A A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20439 530 59237 N114 V S A F L R S N S V R N R V P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39071 444 50417 A46 S N S P S K P A F K H E T K R
Baker's Yeast Sacchar. cerevisiae P24869 491 56228 F36 N N V T N T T F Q K S N A N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 98.6 91.2 N.A. 86.3 84.7 N.A. 75.7 50.5 66.2 61.8 N.A. 34.3 N.A. N.A. N.A.
Protein Similarity: 100 80.5 99.3 94 N.A. 91.9 90.5 N.A. 84.5 66.9 78.2 75.7 N.A. 49.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 66.6 46.6 N.A. 40 13.3 13.3 13.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 66.6 46.6 N.A. 53.3 20 13.3 20 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.4 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 47 8 31 62 31 16 0 0 16 8 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % E
% Phe: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 0 8 8 0 8 39 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 8 8 0 8 8 0 8 62 16 0 0 0 8 0 % K
% Leu: 0 8 0 0 8 0 0 8 0 0 16 47 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 16 0 8 8 0 0 8 0 0 0 16 0 8 8 % N
% Pro: 39 16 0 39 0 8 8 0 8 54 0 8 8 47 8 % P
% Gln: 0 0 0 0 8 0 0 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 8 0 0 8 8 16 8 62 8 62 % R
% Ser: 8 8 8 8 16 0 8 47 8 0 8 0 0 8 0 % S
% Thr: 0 24 8 8 8 8 47 0 0 0 0 0 8 0 8 % T
% Val: 24 16 16 24 16 8 0 0 0 8 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _