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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNB1 All Species: 10.61
Human Site: S69 Identified Species: 19.44
UniProt: P14635 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14635 NP_114172.1 433 48337 S69 M K K E A K P S A T G K V I D
Chimpanzee Pan troglodytes XP_517728 536 59103 S172 M K K E A K P S A T G K V I D
Rhesus Macaque Macaca mulatta XP_001091533 433 48375 S69 M K K E V K P S A T G K V I D
Dog Lupus familis XP_850398 425 47378 A69 L K K E A K T A V P G K V I A
Cat Felis silvestris
Mouse Mus musculus P24860 430 48033 L69 L K R E A K T L G T G K G T V
Rat Rattus norvegicus P30277 423 47373 G67 K K E T K K L G S G T V T V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507609 428 47366 A68 V K K E T K A A V V G K V I P
Chicken Gallus gallus P29332 399 44633 K63 K P P V K A T K G P G K M T N
Frog Xenopus laevis P13350 397 44655 A63 L K P A V K A A K K A K P V D
Zebra Danio Brachydanio rerio NP_571588 398 44818 V66 V A P A A E V V V E K A P V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20439 530 59237 L153 L K R E D S N L S K K S L T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39071 444 50417 T84 V L K D V T N T L A E S I I S
Baker's Yeast Sacchar. cerevisiae P24869 491 56228 R73 F T R E S V S R S T A A Q E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 98.6 91.2 N.A. 86.3 84.7 N.A. 75.7 50.5 66.2 61.8 N.A. 34.3 N.A. N.A. N.A.
Protein Similarity: 100 80.5 99.3 94 N.A. 91.9 90.5 N.A. 84.5 66.9 78.2 75.7 N.A. 49.4 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 60 N.A. 46.6 13.3 N.A. 53.3 13.3 26.6 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 73.3 N.A. 60 33.3 N.A. 66.6 26.6 46.6 26.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.4 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 39 8 16 24 24 8 16 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 31 % D
% Glu: 0 0 8 62 0 8 0 0 0 8 8 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 16 8 54 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 47 0 % I
% Lys: 16 70 47 0 16 62 0 8 8 16 16 62 0 0 16 % K
% Leu: 31 8 0 0 0 0 8 16 8 0 0 0 8 0 0 % L
% Met: 24 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 8 % N
% Pro: 0 8 24 0 0 0 24 0 0 16 0 0 16 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 24 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 8 24 24 0 0 16 0 0 8 % S
% Thr: 0 8 0 8 8 8 24 8 0 39 8 0 8 24 0 % T
% Val: 24 0 0 8 24 8 8 8 24 8 0 8 39 24 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _