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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNB1 All Species: 38.48
Human Site: T276 Identified Species: 70.56
UniProt: P14635 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14635 NP_114172.1 433 48337 T276 F A F V T D N T Y T K H Q I R
Chimpanzee Pan troglodytes XP_517728 536 59103 T379 F A F V T D N T Y T K H Q I R
Rhesus Macaque Macaca mulatta XP_001091533 433 48375 T276 F A F V T D N T Y T K H Q I R
Dog Lupus familis XP_850398 425 47378 T268 F A F V T D N T Y T K H Q I R
Cat Felis silvestris
Mouse Mus musculus P24860 430 48033 T273 F A F V T N N T Y T K H Q I R
Rat Rattus norvegicus P30277 423 47373 T266 F A F V T N N T Y T K H Q I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507609 428 47366 T271 F A F V T D H T Y T K H Q I R
Chicken Gallus gallus P29332 399 44633 A244 F V Y I T D N A Y N S A E V R
Frog Xenopus laevis P13350 397 44655 T242 F T F V T D H T Y T K A Q I R
Zebra Danio Brachydanio rerio NP_571588 398 44818 A243 F A F V T D R A Y T T S Q I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20439 530 59237 T365 F V F I T D D T Y T A R Q I R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39071 444 50417 T288 F C F I T D N T Y T R L E V L
Baker's Yeast Sacchar. cerevisiae P24869 491 56228 A335 F A S E T D G A C T E D E I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 98.6 91.2 N.A. 86.3 84.7 N.A. 75.7 50.5 66.2 61.8 N.A. 34.3 N.A. N.A. N.A.
Protein Similarity: 100 80.5 99.3 94 N.A. 91.9 90.5 N.A. 84.5 66.9 78.2 75.7 N.A. 49.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 40 80 73.3 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 66.6 86.6 73.3 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.4 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 0 0 0 0 0 24 0 0 8 16 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 85 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 8 0 24 0 0 % E
% Phe: 100 0 85 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 16 0 0 0 0 54 0 0 0 % H
% Ile: 0 0 0 24 0 0 0 0 0 0 0 0 0 85 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 62 0 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 16 62 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 77 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 85 % R
% Ser: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % S
% Thr: 0 8 0 0 100 0 0 77 0 93 8 0 0 0 0 % T
% Val: 0 16 0 70 0 0 0 0 0 0 0 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 93 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _