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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL6B
All Species:
16.06
Human Site:
Y143
Identified Species:
35.33
UniProt:
P14649
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14649
NP_002466.1
208
22764
Y143
K
N
R
G
Q
G
T
Y
E
D
Y
L
E
G
F
Chimpanzee
Pan troglodytes
XP_001169268
208
22711
Y143
K
N
R
G
Q
G
T
Y
E
D
Y
L
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001114310
209
22842
Y144
K
N
R
D
Q
G
T
Y
E
D
Y
L
E
G
L
Dog
Lupus familis
XP_848583
209
22934
Y144
K
N
R
D
Q
G
T
Y
E
D
Y
L
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI43
207
22730
Y142
K
N
R
D
Q
G
T
Y
E
D
Y
L
E
G
L
Rat
Rattus norvegicus
Q64119
151
16957
D97
V
E
G
L
R
V
F
D
K
E
G
N
G
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02607
151
16969
D97
V
E
G
L
R
V
F
D
K
E
G
N
G
T
V
Frog
Xenopus laevis
NP_001079458
190
20781
F125
N
N
K
D
Q
G
S
F
E
D
F
V
E
G
L
Zebra Danio
Brachydanio rerio
NP_001005955
151
16919
D97
V
E
G
L
R
V
F
D
K
E
G
N
G
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
D93
I
E
G
L
R
H
F
D
K
D
A
S
G
Y
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53014
153
17126
K99
F
D
K
E
E
T
G
K
I
L
A
A
E
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
93.7
N.A.
91.3
57.2
N.A.
N.A.
53.8
65.3
54.3
N.A.
39.4
N.A.
33.1
N.A.
Protein Similarity:
100
99.5
98.5
96.6
N.A.
94.7
63.4
N.A.
N.A.
62.9
77.4
64.4
N.A.
51.4
N.A.
47.1
N.A.
P-Site Identity:
100
93.3
86.6
86.6
N.A.
86.6
0
N.A.
N.A.
0
46.6
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
86.6
20
N.A.
N.A.
20
80
20
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
37
0
0
0
37
0
64
0
0
0
0
0
% D
% Glu:
0
37
0
10
10
0
0
0
55
28
0
0
64
0
0
% E
% Phe:
10
0
0
0
0
0
37
10
0
0
10
0
0
0
10
% F
% Gly:
0
0
37
19
0
55
10
0
0
0
28
0
37
55
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
46
0
19
0
0
0
0
10
37
0
0
0
0
0
0
% K
% Leu:
0
0
0
37
0
0
0
0
0
10
0
46
0
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
55
0
0
0
0
0
0
0
0
0
28
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
46
0
37
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
46
0
0
0
0
0
0
28
0
% T
% Val:
28
0
0
0
0
28
0
0
0
0
0
10
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
46
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _