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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A4 All Species: 27.88
Human Site: S281 Identified Species: 68.15
UniProt: P14672 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14672 NP_001033.1 509 54787 S281 S L L Q L L G S R T H R Q P L
Chimpanzee Pan troglodytes XP_001169794 509 54797 S281 S L L Q L L G S R T H R Q P L
Rhesus Macaque Macaca mulatta XP_001107391 509 54766 S281 S L L Q L L G S H T H R Q P L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P14142 509 54765 S281 S L L Q L L G S R T H R Q P L
Rat Rattus norvegicus P19357 509 54877 S281 S L L Q L L G S R T H R Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P46896 490 54068 S264 T I M E L F R S P M Y R Q P I
Frog Xenopus laevis NP_001085607 509 55484 S280 S I L Q I F R S R N Y R Q P I
Zebra Danio Brachydanio rerio XP_002662574 489 53575 S264 T I P E L F R S P L Y R Q P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56ZZ7 546 56952 A332 Q G S S E P E A G W F D L F S
Baker's Yeast Sacchar. cerevisiae P38142 488 53507 E276 N R D P E S S E E T H S G P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 N.A. N.A. 95 95.2 N.A. N.A. 63.6 68.5 61.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.6 N.A. N.A. 97.8 97.4 N.A. N.A. 76.4 82.7 76.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 N.A. N.A. 100 100 N.A. N.A. 33.3 53.3 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 N.A. N.A. 100 100 N.A. N.A. 73.3 80 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.3 28 N.A.
Protein Similarity: N.A. N.A. N.A. 47.9 46.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 20 20 0 10 10 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 30 0 0 0 0 10 0 0 10 0 % F
% Gly: 0 10 0 0 0 0 50 0 10 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 60 0 0 0 0 % H
% Ile: 0 30 0 0 10 0 0 0 0 0 0 0 0 0 30 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 50 60 0 70 50 0 0 0 10 0 0 10 0 50 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 10 0 10 0 0 20 0 0 0 0 90 0 % P
% Gln: 10 0 0 60 0 0 0 0 0 0 0 0 80 0 0 % Q
% Arg: 0 10 0 0 0 0 30 0 50 0 0 80 0 0 0 % R
% Ser: 60 0 10 10 0 10 10 80 0 0 0 10 0 0 10 % S
% Thr: 20 0 0 0 0 0 0 0 0 60 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _