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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL1R1
All Species:
17.27
Human Site:
Y388
Identified Species:
54.29
UniProt:
P14778
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14778
NP_000868.1
569
65402
Y388
D
G
K
T
Y
D
A
Y
I
L
Y
P
K
T
V
Chimpanzee
Pan troglodytes
XP_001162875
561
64701
W388
I
L
Y
S
M
Q
R
W
E
G
S
T
S
D
C
Rhesus Macaque
Macaca mulatta
P59822
570
65375
E404
E
T
I
L
D
G
K
E
Y
D
I
Y
V
S
Y
Dog
Lupus familis
XP_538449
730
83041
Y546
D
G
K
T
Y
D
A
Y
I
L
Y
P
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P13504
576
66679
Y391
D
G
K
T
Y
D
A
Y
I
L
Y
P
K
T
L
Rat
Rattus norvegicus
Q02955
576
66740
Y391
D
G
R
T
Y
D
A
Y
V
L
Y
P
K
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514601
573
66108
Y387
D
G
K
T
Y
D
A
Y
I
L
Y
P
K
D
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B6ZK77
700
80295
S410
K
D
Y
D
A
Y
V
S
Y
T
K
V
D
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
25.2
60.5
N.A.
68.4
67
N.A.
52.3
N.A.
N.A.
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
48.5
68
N.A.
81.7
81.4
N.A.
69.9
N.A.
N.A.
43.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
93.3
80
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
63
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
63
13
0
13
13
63
0
0
0
13
0
0
13
25
13
% D
% Glu:
13
0
0
0
0
0
0
13
13
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
63
0
0
0
13
0
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
13
0
0
0
0
0
50
0
13
0
0
0
0
% I
% Lys:
13
0
50
0
0
0
13
0
0
0
13
0
63
0
0
% K
% Leu:
0
13
0
13
0
0
0
0
0
63
0
0
0
0
25
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
63
0
13
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
13
0
0
13
0
13
13
0
% S
% Thr:
0
13
0
63
0
0
0
0
0
13
0
13
0
50
0
% T
% Val:
0
0
0
0
0
0
13
0
13
0
0
13
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
0
0
25
0
63
13
0
63
25
0
63
13
0
0
38
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _