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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL1R1 All Species: 13.94
Human Site: Y426 Identified Species: 43.81
UniProt: P14778 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14778 NP_000868.1 569 65402 Y426 C G Y K L F I Y G R D D Y V G
Chimpanzee Pan troglodytes XP_001162875 561 64701 Y423 F I Y G R D D Y V G E D I V E
Rhesus Macaque Macaca mulatta P59822 570 65375 F440 F G Y K L C I F D R D S L P G
Dog Lupus familis XP_538449 730 83041 Y584 C G Y K L F I Y G R D A Y V G
Cat Felis silvestris
Mouse Mus musculus P13504 576 66679 Y429 F G Y K L F I Y G R D D Y V G
Rat Rattus norvegicus Q02955 576 66740 C429 F G Y K L F I C G R D D Y V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514601 573 66108 Y425 C G Y N L F I Y G R D D L V G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B6ZK77 700 80295 P449 Y G Y K L F I P D R D L I P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 25.2 60.5 N.A. 68.4 67 N.A. 52.3 N.A. N.A. 23.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 48.5 68 N.A. 81.7 81.4 N.A. 69.9 N.A. N.A. 43.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 53.3 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 60 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % A
% Cys: 38 0 0 0 0 13 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 13 0 25 0 88 63 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 13 % E
% Phe: 50 0 0 0 0 75 0 13 0 0 0 0 0 0 0 % F
% Gly: 0 88 0 13 0 0 0 0 63 13 0 0 0 0 75 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 88 0 0 0 0 0 25 0 0 % I
% Lys: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 88 0 0 0 0 0 0 13 25 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 13 0 0 0 0 0 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 88 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % T
% Val: 0 0 0 0 0 0 0 0 13 0 0 0 0 75 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 100 0 0 0 0 63 0 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _