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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP9
All Species:
10
Human Site:
S64
Identified Species:
22
UniProt:
P14780
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14780
NP_004985.2
707
78458
S64
V
A
E
M
R
G
E
S
K
S
L
G
P
A
L
Chimpanzee
Pan troglodytes
XP_514689
699
77734
S64
V
A
E
M
R
G
E
S
K
S
L
G
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001104871
707
78463
S64
V
A
E
M
H
G
D
S
K
S
L
G
P
A
L
Dog
Lupus familis
XP_535300
612
68986
K31
D
T
L
K
K
M
Q
K
F
F
G
L
P
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
P41245
730
80435
K65
A
A
Q
M
M
G
E
K
Q
S
L
R
P
A
L
Rat
Rattus norvegicus
P50282
708
78592
K65
A
A
Q
M
M
G
E
K
Q
S
L
R
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508394
704
78508
G62
F
L
P
L
N
R
L
G
R
A
G
Q
D
L
V
Chicken
Gallus gallus
Q90611
663
74923
L64
C
P
K
D
N
C
N
L
F
V
L
K
D
T
L
Frog
Xenopus laevis
Q10835
469
53622
Zebra Danio
Brachydanio rerio
NP_998288
680
76571
V65
Q
R
S
G
L
Q
A
V
I
S
N
A
K
A
L
Tiger Blowfish
Takifugu rubipres
NP_001032959
677
76300
S65
Q
R
R
S
G
L
D
S
V
I
S
T
K
A
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.3
45.5
N.A.
72.4
74.1
N.A.
46.6
47.2
25.7
58.7
54.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
97
60.9
N.A.
83
84.3
N.A.
62.2
62.6
35.3
74.1
68.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
6.6
N.A.
60
60
N.A.
0
13.3
0
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
73.3
73.3
N.A.
26.6
20
0
20
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
46
0
0
0
0
10
0
0
10
0
10
0
64
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
19
0
0
0
0
0
19
0
0
% D
% Glu:
0
0
28
0
0
0
37
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
19
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
46
0
10
0
0
19
28
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
0
0
28
28
0
0
10
19
0
0
% K
% Leu:
0
10
10
10
10
10
10
10
0
0
55
10
0
10
73
% L
% Met:
0
0
0
46
19
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
0
55
0
0
% P
% Gln:
19
0
19
0
0
10
10
0
19
0
0
10
0
10
0
% Q
% Arg:
0
19
10
0
19
10
0
0
10
0
0
19
0
0
0
% R
% Ser:
0
0
10
10
0
0
0
37
0
55
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
10
% T
% Val:
28
0
0
0
0
0
0
10
10
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _