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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU2F1
All Species:
22.12
Human Site:
S446
Identified Species:
48.67
UniProt:
P14859
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14859
NP_002688.2
743
76472
S446
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Chimpanzee
Pan troglodytes
XP_001157105
807
83962
S510
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Rhesus Macaque
Macaca mulatta
XP_001088884
792
81581
S495
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Dog
Lupus familis
XP_850943
751
77336
S455
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P25425
770
79528
S474
T
P
S
L
V
T
S
S
T
A
T
T
L
T
V
Rat
Rattus norvegicus
P31503
632
65152
P338
S
G
G
T
S
S
S
P
I
K
A
I
F
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513218
725
75703
R427
I
R
V
W
F
C
N
R
R
Q
K
E
K
R
I
Chicken
Gallus gallus
P15143
739
75964
S442
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Frog
Xenopus laevis
P16143
758
78839
S463
P
S
S
G
G
S
S
S
S
P
I
K
S
L
F
Zebra Danio
Brachydanio rerio
P79745
443
47434
A149
P
H
Q
T
H
A
G
A
W
G
S
T
T
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20268
380
42556
P87
P
Q
L
H
F
M
L
P
Q
H
D
W
A
Y
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
93.6
95.4
N.A.
90.3
81.1
N.A.
80.7
96
84
23.4
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
100
91.8
93.8
97.1
N.A.
93.1
83
N.A.
84.2
97.1
90.6
33.1
N.A.
N.A.
N.A.
33.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
6.6
N.A.
13.3
100
33.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
46.6
20
N.A.
13.3
100
40
26.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
10
10
0
10
55
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
19
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
0
10
10
10
55
46
10
0
0
10
0
0
0
0
0
% G
% His:
0
10
0
10
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
10
55
0
0
55
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
10
55
0
0
% K
% Leu:
0
0
10
10
0
0
10
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
73
55
0
0
0
0
0
19
0
10
46
0
0
10
10
% P
% Gln:
0
10
10
0
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
10
0
0
0
0
10
0
% R
% Ser:
10
10
64
46
10
19
28
64
55
46
10
0
10
0
10
% S
% Thr:
10
0
0
19
0
10
46
0
10
0
10
19
10
10
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _