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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPL All Species: 26.06
Human Site: S250 Identified Species: 63.7
UniProt: P14866 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14866 NP_001005335.1 589 64133 S250 S A Q R A K A S L N G A D I Y
Chimpanzee Pan troglodytes XP_001167233 537 59558 S198 S A Q R A K A S L N G A D I Y
Rhesus Macaque Macaca mulatta XP_001085120 558 60215 S219 S A Q R A K A S L N G A D I Y
Dog Lupus familis XP_533677 588 64057 S249 S A Q R A K A S L N G A D I Y
Cat Felis silvestris
Mouse Mus musculus Q8R081 586 63945 S247 S A Q R A K A S L N G A D I Y
Rat Rattus norvegicus Q66H20 531 57470 T193 D N M Y Y P V T L D V L H Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507993 360 40177 S32 Q A M V E F E S V L C A Q K A
Chicken Gallus gallus XP_414998 633 70171 F102 S A K K C V T F A A D E P V Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957393 536 59150 S189 S A Q R A K A S L N G A D I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6ICX4 432 48215 T104 P N R I L L V T I H H M L Y P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 94.7 99.8 N.A. 97.9 22.9 N.A. 36.6 48.1 N.A. 70.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.2 94.7 99.8 N.A. 99.3 41.4 N.A. 45.3 61.2 N.A. 77.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 20 20 N.A. 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 26.6 40 N.A. 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 0 0 60 0 60 0 10 10 0 70 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 10 0 60 0 0 % D
% Glu: 0 0 0 0 10 0 10 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 10 0 10 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 0 0 60 10 % I
% Lys: 0 0 10 10 0 60 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 10 10 0 0 70 10 0 10 10 0 0 % L
% Met: 0 0 20 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 20 0 0 0 0 0 0 0 60 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % P
% Gln: 10 0 60 0 0 0 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 10 60 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 70 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 10 20 0 10 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _