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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DARS
All Species:
44.55
Human Site:
S458
Identified Species:
81.67
UniProt:
P14868
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14868
NP_001340.2
501
57136
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Chimpanzee
Pan troglodytes
XP_515810
501
57148
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001095858
501
57030
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Dog
Lupus familis
XP_848666
501
57056
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q922B2
501
57099
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Rat
Rattus norvegicus
P15178
501
57108
S458
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006528
503
57186
S460
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Frog
Xenopus laevis
NP_001080336
530
60145
S487
K
I
K
A
Y
I
D
S
F
R
F
G
A
P
P
Zebra Danio
Brachydanio rerio
NP_001071079
531
60534
S488
K
I
K
A
Y
I
D
S
F
R
Y
G
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476609
531
59041
S488
K
I
A
A
Y
I
E
S
F
R
Y
G
C
P
P
Honey Bee
Apis mellifera
XP_393437
533
60499
A490
K
I
K
S
Y
I
D
A
F
K
Y
G
C
P
P
Nematode Worm
Caenorhab. elegans
Q03577
531
59921
S488
K
I
Q
S
Y
I
D
S
F
K
Y
G
C
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04802
557
63497
G514
G
L
K
D
Y
C
D
G
F
S
Y
G
C
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
97.4
N.A.
96.2
95.6
N.A.
N.A.
89.6
84.7
79
N.A.
63.6
63
60.6
N.A.
Protein Similarity:
100
99.8
98.1
99
N.A.
99
98.8
N.A.
N.A.
94.4
89.8
87.3
N.A.
77.4
78
75.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
73.3
66.6
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
52.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
65.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
77
0
0
0
8
0
0
0
0
70
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
31
0
0
% C
% Asp:
0
0
0
8
0
0
93
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
62
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
93
0
0
0
93
0
0
0
0
0
0
0
0
0
% I
% Lys:
93
0
85
0
0
0
0
0
0
16
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
100
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% R
% Ser:
0
0
0
16
0
0
0
85
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
100
0
0
0
0
0
39
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _