KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO1
All Species:
17.58
Human Site:
S322
Identified Species:
35.15
UniProt:
P14902
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14902
NP_002155.1
403
45326
S322
S
V
R
E
F
V
L
S
K
G
D
A
G
L
R
Chimpanzee
Pan troglodytes
XP_001137363
403
45217
S322
S
V
R
E
F
V
L
S
K
G
D
A
G
L
R
Rhesus Macaque
Macaca mulatta
NP_001070951
403
45435
S322
S
V
R
E
F
V
L
S
K
G
D
A
G
L
R
Dog
Lupus familis
XP_532793
407
46194
S326
S
V
R
E
F
V
R
S
R
D
D
V
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P28776
407
45623
S326
P
V
R
E
F
V
I
S
R
H
N
E
D
L
T
Rat
Rattus norvegicus
Q9ERD9
407
45812
L326
P
V
R
E
F
V
I
L
R
R
N
E
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
G306
S
E
N
S
Q
L
Y
G
A
Y
N
K
C
V
T
Chicken
Gallus gallus
XP_424397
362
39942
A282
R
Q
H
I
L
S
S
A
D
P
Q
L
R
E
A
Frog
Xenopus laevis
NP_001091286
398
44646
E315
S
L
P
G
Y
V
Q
E
S
G
D
P
E
L
L
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
D332
E
R
L
T
H
A
F
D
K
C
V
A
G
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
S335
S
I
K
D
Y
I
H
S
S
D
S
P
E
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
R350
N
I
R
E
Y
V
S
R
N
A
S
N
R
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.5
66.5
N.A.
61.1
62.4
N.A.
42.9
40.2
42.6
42.5
N.A.
N.A.
N.A.
N.A.
28.5
Protein Similarity:
100
99.2
96.2
81
N.A.
76.1
76.6
N.A.
63.2
57
62.5
61.1
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
100
100
60
N.A.
46.6
40
N.A.
6.6
0
33.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
26.6
6.6
46.6
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
9
9
0
34
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
9
17
42
0
17
0
0
% D
% Glu:
9
9
0
59
0
0
0
9
0
0
0
17
25
9
0
% E
% Phe:
0
0
0
0
50
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
0
34
0
0
34
0
0
% G
% His:
0
0
9
0
9
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
17
0
9
0
9
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
34
0
0
9
0
0
17
% K
% Leu:
0
9
9
0
9
9
25
9
0
0
0
9
0
67
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
9
0
25
9
0
0
0
% N
% Pro:
17
0
9
0
0
0
0
0
0
9
0
17
0
0
0
% P
% Gln:
0
9
0
0
9
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
9
9
59
0
0
0
9
9
25
9
0
0
17
0
25
% R
% Ser:
59
0
0
9
0
9
17
50
17
0
17
0
0
9
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
0
50
0
0
0
67
0
0
0
0
9
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _