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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDO1
All Species:
14.55
Human Site:
S359
Identified Species:
29.09
UniProt:
P14902
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14902
NP_002155.1
403
45326
S359
K
Y
I
L
I
P
A
S
Q
Q
P
K
E
N
K
Chimpanzee
Pan troglodytes
XP_001137363
403
45217
S359
K
Y
I
L
I
P
A
S
Q
Q
P
K
E
N
K
Rhesus Macaque
Macaca mulatta
NP_001070951
403
45435
S359
K
Y
I
L
I
P
A
S
Q
Q
P
K
E
N
K
Dog
Lupus familis
XP_532793
407
46194
S363
K
Y
I
V
I
P
A
S
Q
Q
P
K
N
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P28776
407
45623
K363
T
Y
I
M
K
P
S
K
K
K
P
T
D
G
D
Rat
Rattus norvegicus
Q9ERD9
407
45812
K363
T
Y
I
V
K
P
S
K
Q
K
P
M
G
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516166
388
42890
K343
N
A
K
A
N
R
G
K
P
D
Q
Q
L
G
H
Chicken
Gallus gallus
XP_424397
362
39942
A319
I
A
V
A
K
A
K
A
G
Q
K
E
A
G
S
Frog
Xenopus laevis
NP_001091286
398
44646
N352
K
Y
V
S
A
A
G
N
R
S
K
M
L
G
K
Zebra Danio
Brachydanio rerio
NP_001077323
435
48931
N369
Q
L
R
A
N
K
Q
N
L
M
E
E
L
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782741
463
51327
H372
R
F
I
I
N
M
A
H
Q
K
T
G
P
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47125
453
50757
S387
T
K
Y
I
I
L
P
S
N
S
K
Q
H
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.5
66.5
N.A.
61.1
62.4
N.A.
42.9
40.2
42.6
42.5
N.A.
N.A.
N.A.
N.A.
28.5
Protein Similarity:
100
99.2
96.2
81
N.A.
76.1
76.6
N.A.
63.2
57
62.5
61.1
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
100
100
80
N.A.
26.6
33.3
N.A.
0
6.6
20
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
60
53.3
N.A.
6.6
26.6
40
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
25
9
17
42
9
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
17
25
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
9
0
0
9
9
59
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
17
% H
% Ile:
9
0
59
17
42
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
42
9
9
0
25
9
9
25
9
25
25
34
0
0
34
% K
% Leu:
0
9
0
25
0
9
0
0
9
0
0
0
25
0
0
% L
% Met:
0
0
0
9
0
9
0
0
0
9
0
17
0
0
0
% M
% Asn:
9
0
0
0
25
0
0
17
9
0
0
0
9
34
0
% N
% Pro:
0
0
0
0
0
50
9
0
9
0
50
0
9
0
0
% P
% Gln:
9
0
0
0
0
0
9
0
50
42
9
17
0
0
9
% Q
% Arg:
9
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
17
42
0
17
0
0
0
0
25
% S
% Thr:
25
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% T
% Val:
0
0
17
17
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _