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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAO All Species: 31.21
Human Site: Y144 Identified Species: 68.67
UniProt: P14920 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14920 NP_001908.3 347 39474 Y144 L I L E G K N Y L Q W L T E R
Chimpanzee Pan troglodytes XP_001164250 232 26431 N61 P Y L S D P N N P Q E A D W S
Rhesus Macaque Macaca mulatta XP_001103664 347 39422 Y144 L I L E G K N Y L Q W L T E R
Dog Lupus familis XP_543443 347 39116 Y144 L I V E G R R Y L E W L T K R
Cat Felis silvestris
Mouse Mus musculus P18894 345 38643 Y143 L L L E G K S Y L P W L T E R
Rat Rattus norvegicus O35078 346 38802 Y143 L L L E G K S Y L S W L T E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513322 308 34485 L137 Y G W F N T A L I L E G K S Y
Chicken Gallus gallus XP_415185 362 40818 Y144 L M L E C R S Y L P W L T N R
Frog Xenopus laevis NP_001090031 347 39281 Y144 I M I E G K H Y L P W M M K R
Zebra Danio Brachydanio rerio NP_001028912 348 39300 Y144 L V I E G K S Y L P W L M D W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95XG9 322 36099 Y140 W Y L E P T P Y I K W C T D K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.4 94.5 83.2 N.A. 80.6 80.4 N.A. 63.6 61.8 62.2 58.9 N.A. N.A. N.A. 35.7 N.A.
Protein Similarity: 100 66.2 97.6 91.6 N.A. 90.1 89.6 N.A. 75.5 78.1 80.4 80.1 N.A. N.A. N.A. 56.4 N.A.
P-Site Identity: 100 20 100 66.6 N.A. 80 80 N.A. 0 60 46.6 53.3 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 93.3 93.3 N.A. 6.6 80 86.6 80 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 0 10 19 0 % D
% Glu: 0 0 0 82 0 0 0 0 0 10 19 0 0 37 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 64 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 28 19 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 55 0 0 0 10 0 0 10 19 10 % K
% Leu: 64 19 64 0 0 0 0 10 73 10 0 64 0 0 0 % L
% Met: 0 19 0 0 0 0 0 0 0 0 0 10 19 0 0 % M
% Asn: 0 0 0 0 10 0 28 10 0 0 0 0 0 10 0 % N
% Pro: 10 0 0 0 10 10 10 0 10 37 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 10 0 0 0 0 0 0 0 64 % R
% Ser: 0 0 0 10 0 0 37 0 0 10 0 0 0 10 10 % S
% Thr: 0 0 0 0 0 19 0 0 0 0 0 0 64 0 0 % T
% Val: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 10 0 0 0 0 0 0 0 82 0 0 10 10 % W
% Tyr: 10 19 0 0 0 0 0 82 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _